Results 231 to 240 of about 343,599 (390)

The transmembrane amyloid precursor C99 protein exhibits non-specific interaction with tau

, 2021
Rhett J. Britton, J.M.S. Hutchison, Charles R. Sanders   +2 more
openalex   +2 more sources

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression [PDF]

, 2019
Bateman, Randall J.
core   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein

, 1998
Peizhong Zheng, Jean Eastman, Scott Vande Pol, Sanjay W. Pimplikar   +3 more
openalex   +2 more sources

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Amyloid precursor protein accumulation in glioblastoma is associated with altered synaptic dynamics and immune suppression. [PDF]

Discov Oncol
Porter TR, Inyushin M, Kucheryavykh L.
europepmc   +1 more source

Secretory cleavage site of Alzheimer amyloid precursor protein is heterogeneous in Down's syndrome brain [PDF]

, 1994
Fuyuki Kametania, Kikuko Tanaka, Takahiko Tokuda, Shu‐ichi Ikeda   +3 more
openalex   +1 more source

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.

Proceedings of the National Academy of Sciences of the United States of America, 1999
S. Lammich, E. Kojro, R. Postina, S. Gilbert, R. Pfeiffer, M. Jasionowski, C. Haass, F. Fahrenholz   +7 more
semanticscholar   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents. [PDF]

PLoS Biol
Ji MJ, Wu TX, Tian C, Cao X, Wei R, Yang YY, Meng X, Tang H, Cui T, Yang J, Tang X, Liu C.   +11 more
europepmc   +1 more source