Results 261 to 270 of about 343,599 (390)

The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes

Acta Neuropathologica, 2014
H. Nhan, K. Chiang, E. Koo
semanticscholar   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Iron responsive elements mRNA regulate Alzheimer's amyloid precursor protein translation through iron sensing. [PDF]

Front Aging Neurosci
Khan MA.
europepmc   +1 more source

Composition, Techno‐Functional Properties, and Biological Potential of Velvet and African Yam Beans as Plant Protein Sources

Sustainable Food Proteins, Volume 4, Issue 1, March 2026.
Graphical Overview of Protein quality characterization of velvet and African yam beans. ABSTRACT The increasing demand for plant‐based foods has intensified research in alternative protein sources. This study assessed the chemical composition, functional properties, and biological qualities of velvet bean (VB) and African yam bean (AYB) flours to ...
Chiemeziem Adanma Obike, Paul Ndubuisi Anyiam, Chinedum Uche Emelike, Emmanuel Nnaemeka Uhuo, Solomon Fanyam Igbazenda   +4 more
wiley   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

Modeling presynaptic inhibition by the amyloid precursor protein demonstrates one potential mechanism for preventing runaway synaptic modification in Alzheimer's disease. [PDF]

Alzheimers Dement
Barber D, Hasselmo ME, Rice HC.
europepmc   +1 more source

Peptide and Drug‐Protected Gold Nanoclusters as Promising Biomaterials: Synthesis, Properties, and Applications

Aggregate, Volume 7, Issue 2, February 2026.
The integration of atomically precise gold nanoclusters with peptides or drugs represents a cutting‐edge class of nanomaterials in the biomedical field, owing to their unique physicochemical properties such as water solubility, excellent biocompatibility, low toxicity, and good renal clearance.
Rebeca Garcia Moura, M. Terêsa Machini, Rongchao Jin   +2 more
wiley   +1 more source

Detergent-free isolation and characterization of amyloid precursor protein C99 in E. coli native lipid-nanodiscs using non-ionic polymer. [PDF]

Protein Sci
Sharma G, Krishnarjuna B, Hiiuk VM, Ivanova MI, Nagorny P, Ramamoorthy A.   +5 more
europepmc   +1 more source

The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

Neuron, 1995
A. Iwai, E. Masliah, M. Yoshimoto, N. Ge, L. Flanagan, H. D. Silva, Á. Kittel, T. Saitoh   +7 more
semanticscholar   +1 more source

Amyloid Beta Precursor Protein Measurement [PDF]

, 2020
openaire   +1 more source