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Secretase Processing of Amyloid Precursor Protein (APP) and Neurodegeneration
2007N. Marks, M. J. Berg
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Proteolytic processing of the amyloid precursor protein by α-secretase
Biochemical Society Transactions, 2002T. M. J. Allinson +2 more
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A study of b-secretase cleaved Alzheimer amyloid precursor protein
2002Alzheimer's disease (AD) is characterized by the degeneration and loss of neurons, intracellular neurofibrillary tangles and the accumulation of extracellular senile plaques consisting mainly of beta-amyloid (A-beta). A-beta is generated from the amyloid precursor protein (APP) through sequential cleavage by proteases P- and gamma-secretase ...
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Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation
Chemical Reviews, 2018Huan-Xiang Zhou, Xiaodong Pang
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Characterization of “secretase”, Alzheimer amyloid protein precursor secreting enzyme
Neurobiology of Aging, 1992openaire +1 more source
Coarse-Grained Protein Models and Their Applications
Chemical Reviews, 2016Sebastian Kmiecik +2 more
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The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
Science, 2002John Hardy
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The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Science, 2011Peter Walter, David Ron
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Biochemistry of Peroxynitrite and Protein Tyrosine Nitration
Chemical Reviews, 2018Gerardo Ferrer-Sueta +2 more
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