Results 141 to 150 of about 98,806 (295)

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Endoscopic Diagnosis and Clinical Course of Isolated Upper Gastrointestinal Amyloidosis: A Retrospective Observational Study. [PDF]

Korean J Helicobacter Up Gastrointest Res
Kim JS, Seo YE, Lim CJ, Im CM, Oh HH, Kim KH, Cho SB, Koo JY, Joo YE, Lee WS.   +9 more
europepmc   +1 more source

Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models

VIEW, EarlyView.
Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley   +1 more source

A Case of AL Amyloidosis With Hepatomegaly as the Main Clinical Manifestation. [PDF]

Clin Case Rep
Dong S, Lv R, Wang W, Gao G, Zhao M, Ma X.   +5 more
europepmc   +1 more source

Prognostic value of exercise echocardiography in patients with wild-type transthyretin amyloidosis

, 2022
Cristina Aguilera Agudo, Vanessa Moñivas Palomero, Esther González López, Susana Mingo Santos   +3 more
openalex   +2 more sources

PBX1 Improves Cognition and Reduces Amyloid‐β Pathology in APP/PS1 Mice by Transcriptionally Activating the CRTC2–CREB Pathway

Aging Cell, EarlyView.
We found that the transcription factor PBX1 is markedly downregulated in patients with Alzheimer's disease and in disease models. Restoring PBX1 reduces Aβ pathology and rescues cognitive deficits. Mechanistically, PBX1 directly activates the transcription of CRTC2 and enhances p‐CREB signaling, thereby conferring neuroprotection.
Zinan Liu, Xiangyuan Meng, Rifeng Lu, Xiaoting Meng, Siyao Li, Yujie Wang, Xinpeng Liu, Xiaomei Liu, Jinyu Liu   +8 more
wiley   +1 more source

Amyloid A Amyloidosis Secondary to Thymoma. [PDF]

Diagnostics (Basel)
Li M, Yao S, Zeng L, Wang J.
europepmc   +1 more source

Causes of AA amyloidosis: a systematic review [PDF]

, 2019
Anne F. Brunger, Hans Nienhuis, Johan Bijzet, Bouke P. C. Hazenberg   +3 more
openalex   +1 more source

The incidence of serious complications after selective laser trabeculoplasty

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the incidence of serious complications after selective laser trabeculoplasty (SLT). Methods All patients who underwent SLT at the Department of Ophthalmology, Helsinki University Hospital, were eligible for the study from 1 January 2012 to 31 December 2018.
Eeva S. Ojanen, Joni A. Turunen, Mika Harju   +2 more
wiley   +1 more source

Coronary microvascular dysfunction as an initial clue to the diagnosis of light-chain amyloidosis: a case report. [PDF]

Eur Heart J Case Rep
Bando R, Yagi S, Kadota M, Ise T, Sata M.   +4 more
europepmc   +1 more source