Results 41 to 50 of about 3,472 (209)

In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses

Frontiers in Cellular and Infection Microbiology, 2022
Dengue and chikungunya are two important mosquito-borne infections which are known to occur extensively in tropical and subtropical areas. Presently, there is no treatment for these viral diseases.
Kalichamy Alagarasu, Poonam Patil, Meenakshi Kaushik, Deepika Chowdhury, Rajesh K. Joshi, Harsha V. Hegde, Mahadeo B. Kakade, Sugeerappa Laxmanappa Hoti, Sarah Cherian, Deepti Parashar   +9 more
doaj   +1 more source

New Anacardic Acid‐Inspired Benzamides: Histone Lysine Acetyltransferase Activators [PDF]

ChemMedChem, 2010
AbstractA series of N‐(4‐cyano‐3‐trifluoromethyl‐phenyl)‐2‐ethoxy‐6‐alkyl (and alkenyl) benzamides related to the anacardic acid derivative CTPB have been prepared from 2,6‐dihydroxybenzoic acid with a Suzuki coupling and addition of the anion of 4‐cyano‐3‐trifluoromethylphenylamine to a benzodioxinone as the key steps.
SOUTO JA, BENEDETTI R, OTTO K, MICELI M, ALVAREZ R, ALTUCCI, Lucia, DE LERA AR   +6 more
openaire   +4 more sources

Inhibition of PCAF Histone Acetyltransferase, Cytotoxicity and Cell Permeability of 2-Acylamino-1-(3- or 4-Carboxy-phenyl)benzamides

Molecules, 2012
Small molecule HAT inhibitors are useful tools to unravel the role of histone acetyltransferases (HATs) in the cell and they also have relevance in oncology.
Eunsook Ma, Woong Jae Park
doaj   +1 more source

Structure-activity relationships on cynnamoyl derivatives as inhibitors of p300 Histone acetyltransferase [PDF]

, 2017
Human p300 is a polyhedric transcriptional coactivator, playing a crucial role by acetylating histones on specific lysine residues. A great deal of evidences shows that p300 is involved in several diseases as leukemia, tumors and viral infection.
Alberter, Arif, Artico, Azoulay, Balasubramanyam, Barreca, Brown, Chen, Choi, Costi, Costi, Dekker, Devipriya, Eckner, Farid, Gao, Getun, Ghizzoni, Granchi, Iyer, Iyer, Iyer, Kurdistani, Ligeret, Liu, Maddox, Mai, Maksimoska, Marcu, Noh, Osman, Ravindra, Robles, Sherman, Sherman, Sterner, Stimson, Thompson, Tintori, Toth, Tuccinardi, Valor, Vempati, Wang, Wong, Yasufumi, Zhao, Zheng, Zheng, Zhu   +49 more
core   +1 more source

Effects of cashew nutshell extract and monensin on microbial fermentation in a dual-flow continuous culture

Journal of Dairy Science, 2023
: The objective of this study was to compare cashew nutshell extract (CNSE) to monensin and evaluate changes in in vitro mixed ruminal microorganism fermentation, nutrient digestibility, and microbial nitrogen outflow.
E. Sarmikasoglou, M.L. Johnson, J.R. Vinyard, P. Sumadong, R.R. Lobo, J.A. Arce-Cordero, A. Bahman, A. Ravelo, S. Halima, G.K. Salas-Solis, C. Hikita, T. Watanabe, A.P. Faciola   +12 more
doaj   +1 more source

Influence of leaf trichome type, and density on the host plant selection by the greenhouse whitefly, Trialeurodes vaporariorum (Hemiptera: Aleyrodidae) [PDF]

, 2014
Host selection by adult greenhouse whitefly Trialeurodes vaporariorum (Westwood) was assessed on two pelargonium plant cultivars, Pelargonium x domesticum (regal) and P. x hortorum (zonal) using Petri dish bioassay chambers in choice and no-choice tests.
AH Medeiros, AL Lambert, AT Simmons, AT Simmons, B Mamba, C Castañé, C Maliepaard, C Soria, CC Chu, D Gilrein, D Riley, DG Riley, DJ Schultz, DL Gerhold, DN Byrne, DS Walters, DS Walters, G Boiteau, GD Butler Jr, H Lei, H Lei, HC Wen, HJ McAuslane, IEA Salem, J Mithila, Jane Faull, JC Lenteren van, JJA Walt van der, JP Sanderson, JW Neal Jr, KM Heinz, LJ Laughner, M Aslam, M Inbar, M Lis-Balchin, Monique S. J. Simmonds, MSJ Simmonds, ORC Campos, P Sánchez-Peña, Pasco B. Avery, R Malakar, R Xu, RL Meagher, TE Bilderback, Vivek Kumar, WA Erb, ZT Dabrowski   +46 more
core   +1 more source

Teores de ácido anacárdico em pedúnculos de cajueiro Anacardium microcarpum e em oito clones de Anacardium occidentale var. nanum disponíveis no Nordeste do Brasil Anacardic acid content in cashew apples from Annacardium microcarpum and eight clones of Anacardium occidentale from Northeastern Brazil

Ciência Rural, 2004
O ácido anacárdico, composto fenólico presente em pedúnculos de caju e em algumas plantas medicinais, vem sendo associado a uma série de atividades biológicas específicas.
Tânia da Silveira Agostini-Costa, Katiane Arrais Jales, Deborah dos Santos Garruti, Viviane Azevedo Padilha, Jedaias Batista de Lima, Maria de Jesus Aguiar, João Rodrigues de Paiva   +6 more
doaj   +1 more source

Histone deacetylases suppress cgg repeat-induced neurodegeneration via transcriptional silencing in models of Fragile X Tremor Ataxia Syndrome [PDF]

, 2010
Fragile X Tremor Ataxia Syndrome (FXTAS) is a common inherited neurodegenerative disorder caused by expansion of a CGG trinucleotide repeat in the 59UTR of the fragile X syndrome (FXS) gene, FMR1.
A Entezam, AL Barlow, Amy Krans, B Coffee, B Coffee, B Primerano, BD Strahl, C Ito, C Sellier, CH Liao, Christopher E. Pearson, CK Iwahashi, CM Greco, CM Greco, CM Greco, D Garcia-Arocena, D Grafodatskaya, DG Arocena, DJ Mulvihill, E Berry-Kravis, E Peprah, E Rodriguez-Lebron, E Tabolacci, E Tabolacci, E Tabolacci, EP Brennan, F Tassone, F Tassone, F Tassone, F Tassone, F Tassone, G Du, Henry L. Paulson, HR Acevedo, IK Hornstra, J Pallos, J. Paul Taylor, JB Zang, JP Thomson, JR Brouwer, JR Brouwer, JS Steffan, JS Sutcliffe, K Balasubramanyam, K Balasubramanyam, K Usdin, Kyung-Tai Min, L Rodriguez-Revenga, LS Chen, M Habib, M Torrioli, MD Shahbazian, MH Pan, NB Nedelsky, Nicholas A. Di Prospero, OA Sofola, OA Sofola, P Jin, P Jin, P Kazemi-Esfarjani, PD Ladd, Peter K. Todd, PJ Hagerman, PK Todd, PR Kramer, R Biacsi, R Pietrobono, R Willemsen, S Jacquemont, SE McGuire, Seok Yoon Oh, SR Patel, SS Chong, T Osterwalder, T Tanaka, UB Pandey, Udai B. Pandey, V Handa, V Hashem, Y Cho, Y Feng, YH Wang   +81 more
core   +3 more sources

Design of chitosan-alginate core-shell nanoparticules loaded with anacardic acid and cardol for drug delivery [PDF]

Polímeros, 2020
Anacardic Acid (AA) and Cardol (CD) are the main constituents of the cashew nut shell liquid, which presented several biological activities. In this study, a 23 factorial experimental design was employed in order to evaluate the influence of the reaction
João Campos Paiva Filho, Selene Maia de Morais, Antonio Carlos Nogueira Sobrinho, Gessica Soares Cavalcante, Nilvan Alves da Silva, Flávia Oliveira Monteiro da Silva Abreu   +5 more
doaj   +1 more source

Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice [PDF]

, 2017
AIMS: To investigate the hypothesis that alteration in histone acetylation/deacetylation triggers aberrant STAT1/MyD88 expression in macrophages from diabetics.
Brandt, Stephanie L., Filgueiras, Luciano Ribeiro, Jancar, Sonia, Oliveira Ramalho, Theresa Raquel de, Serezani, C. Henrique   +4 more
core   +1 more source