Results 121 to 130 of about 335,029 (357)
Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion [PDF]
arXiv, 2008 Tumour progression has been described as a sequence of traits or phenotypes that cells have to acquire if the neoplasm is to become an invasive and malignant cancer. Although the genetic mutations that lead to these phenotypes are random, the process by which some of these mutations become successful and spread is influenced by the tumour ...
arxiv
LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
, 2014 The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart +7 more
core +2 more sources
Animal Models and Experimental Medicine, EarlyView.Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao +6 more
wiley +1 more source
Glycolytic activity of the tissue stem cells in the macula flava of the human vocal fold
Laryngoscope Investigative Otolaryngology, 2021 Objectives In our previous studies, the features of the mitochondria of tissue stem cells in the maculae flavae of the human vocal fold suggested that their metabolic activity and oxidative phosphorylation was low.
Kiminori Sato +5 more
doaj +1 more source
Effects of Low pH on Lactate Dehydrogenase Kinetics of Diving and Nondiving Reptiles [PDF]
, 1986 The properties of lactate dehydrogenase were examined in two snake species, Nerodia rhombifera and Elaphe obsoleta, and a turtle species, Pseudemys scripta.
Baeyens, Dennis A., Hurley, Salim R.
core +2 more sources
Frequency Domain Properties and Fundamental Limits of Buffer-Feedback Regulation in Biochemical Systems [PDF]
arXiv, 2018 Feedback regulation in biochemical systems is fundamental to homeostasis, with failure causing disease or death. Recent work has found that cooperation between feedback and buffering---the use of reservoirs of molecules to maintain molecular concentrations---is often critical for biochemical regulation, and that buffering can act as a derivative or ...
arxiv
Dynamic scenario of metabolic pathway adaptation in tumors and therapeutic approach [PDF]
, 2015 Cancer cells need to regulate their metabolic program to fuel several activities, including unlimited proliferation, resistance to cell death, invasion and metastasis. The aim of this work is to revise this complex scenario.
Bianchini, Francesca +2 more
core +2 more sources
Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
BMEMat, EarlyView.This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen +6 more
wiley +1 more source
Plastic recycling: Challenges and opportunities
The Canadian Journal of Chemical Engineering, EarlyView.Abstract This review offers an in‐depth exploration of current strategies for recycling plastic waste, focusing on mechanical, chemical, and energy recovery methods. It situates these strategies within the context of modern practices by examining ongoing research methodologies and specific case studies related to various types of plastic waste.
Pradeep Sambyal +6 more
wiley +1 more source
Metabolic changes during cardiac regeneration in the axolotl
Developmental Dynamics, EarlyView.Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich +10 more
wiley +1 more source