Results 61 to 70 of about 395,234 (289)

Association of red blood cell distribution width with short- and long-term all-cause mortality in patients with acute pancreatitis and sepsis

BMC Gastroenterology
Background The association between red blood cell distribution width (RDW) and short- and long-term all-cause mortality in patients with acute pancreatitis (AP) and sepsis remains unclear.
Qingzhou Song, Xuanlin Wu, Firooz Ahmad Taheri, Linghou Meng, Wentao Wang, Xianwei Mo   +5 more
doaj   +1 more source

Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer

mSystems
This study focuses on the significant role between gut microbiota and lymph node metastasis (LNM) in colorectal cancer (CRC). By conducting 16S rRNA sequencing on fecal samples from 147 CRC patients and combining it with the linear discriminant analysis ...
Yongzhi Wu, Chengen Deng, Zigui Huang, Yongqi Huang, Chuanbin Chen, Mingjian Qin, Zhen Wang, Fuhai He, Shenghai Liu, Rumao Zhong, Jun Liu, Chenyan Long, Jungang Liu, Weizhong Tang, Xiaoliang Huang   +14 more
doaj   +1 more source

Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]

, 2017
The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu, Cui, Li, Hu, Shen, Ji, Eoon Hye, Messadi, Diana, Yan, Xinmin, Yuan, Xiaoqing   +6 more
core   +1 more source

Mature Tertiary Lymphoid Structures Indicate Good Chemotherapy Response and Prognosis in Advanced Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
In advanced colorectal cancer, tumors with mature tertiary lymphoid structures (TLS) exhibited abundant infiltration of CD3‐ and CD8‐positive lymphocytes in both primary and metastatic sites, indicating an activated immune response. The presence of mature TLS was also associated with favorable chemotherapy sensitivity and improved prognosis.
Nobuhiro Hosoi, Chika Komine, Gendensuren Dorjkhorloo, Takuya Shiraishi, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Takehiko Yokobori, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Exploring the gut microbiota associated with peripheral nerve invasion in colorectal cancer patients and constructing predictive models

BMC Microbiology
Objective This study aims to explore the differences in composition, abundance, and biological functions of the gut microbiota between colorectal cancer (CRC) patients with peripheral nerve invasion (PNI) and those without peripheral nerve invasion (NPNI)
Chuanbin Chen, Qingmin Chen, Shenghai Liu, Guoxi Li, Jiawei Zhao, Jingting Huang, Tianyi Ye, Xinting Yang, Zigui Huang, Zhen Wang, Fuhai He, Mingjian Qin, Chenyan Long, Binzhe Tang, Yongqi Huang, Weizhong Tang, Jungang Liu, Xiaoliang Huang   +17 more
doaj   +1 more source

Identification and predictive machine learning model construction of gut microbiota associated with carcinoembryonic antigens in colorectal cancer

mSphere
Carcinoembryonic antigen (CEA) is a critical colorectal cancer (CRC) biomarker, but its mechanistic link to gut microbiota remains unclear. This study characterized gut microbiota differences between high-CEA (H-CEA) and low-CEA (L-CEA) CRC patients and ...
Yongzhi Wu, Zigui Huang, Yongqi Huang, Chuanbin Chen, Mingjian Qin, Zhen Wang, Fuhai He, Shenghai Liu, Rumao Zhong, Jun Liu, Chenyan Long, Jungang Liu, Xiaoliang Huang   +12 more
doaj   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Takahide Shinagawa, Soichiro Ishihara   +9 more
wiley   +1 more source

Who Knows Best What the Next Year Will Hold for You? The Validity of Direct and Personality‐based Predictions of Future Life Experiences Across Different Perceivers

European Journal of Personality, EarlyView., 2020
Abstract This study explored the validity of person judgements by targets and their acquaintances (‘informants’) in longitudinally predicting a broad range of psychologically meaningful life experiences. Judgements were gathered from four sources (targets, N = 189; and three types of informants, N = 1352), and their relative predictive validity was ...
Nele M. Wessels, Johannes Zimmermann, Daniel Leising, Jan‐Erik Lönnqvist   +3 more
wiley   +1 more source

Arginase 2 Promotes Colorectal Cancer Metastasis via PI3K/AKT Pathway Activation and Regulates Tumor Immune Infiltration

Cancer Medicine
Background Colorectal cancer (CRC) is a leading cause of cancer‐related deaths, with metabolic reprogramming involved in its pathogenesis. Aberrant Arginase 2 (ARG2) expression is linked to malignant progression, but its role in CRC remains unclear ...
Yueyan Zhang, Ning Qu, Jiale Mei, Caixia Mo, Luojuan Wei, Haixian Shen, Shanfei Zhou, Jinmin Hu, Wenqi Luo, Xianwei Mo   +9 more
doaj   +1 more source

Multifractal characteristics of external anal sphincter based on sEMG signals

, 2017
This work presents the application of Multifractal Detrended Fluctuation Analysis for the surface electromyography signals obtained from the patients suffering from rectal cancer.
Machura, Lukasz, Nowakowski, Michal, Trybek, Paulina   +2 more
core   +1 more source