Results 141 to 150 of about 353,256 (314)
Advanced Science, EarlyView.Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu +20 more
wiley +1 more source
The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression
Advanced Science, EarlyView.LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao +7 more
wiley +1 more source
High‐Density Flexible Neural Implants with Submicron Feedline Resolution
Advanced Electronic Materials, EarlyView.Optimization of microfabrication methods using optical contact lithography (OCL) and electron beam lithography (EBL) enables the fabrication of 64‐channel, high‐density, parylene‐C‐based intracortical implants with submicron feedlines as narrow as 400 and 50 nm, respectively.
Lina Koschinski +10 more
wiley +1 more source
Coronavirus and analgesics [PDF]
British Dental Journal, 2020 Skoglund, L. A. +2 more
openaire +3 more sources
Annals of Gastroenterological Surgery, EarlyView.We retrospectively compared intracorporeal and extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer in 46 institutions by using propensity‐score matching. Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury, bowel recovery, and length of
Tomohiro Yamaguchi +92 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2002 N. Chandrasekharan +6 more
semanticscholar +1 more source
Artificial Intelligences: A Bridge Toward Diverse Intelligence and Humanity's Future
Advanced Intelligent Systems, EarlyView.Many discussions of artificial intelligence fail to address deeper questions being raised by advances in developmental biology, neuroscience, bioengineering, and philosophy of mind. Novel beings, including technologically and biologically augmented humans, engineered life forms, hybrots, and others, require tools of the emerging field of diverse ...
Michael Levin
wiley +1 more source