Results 171 to 180 of about 625,843 (401)
CHLORPROMAZINE (“LARGACTIL”) AS AN ANALGESIC IN LABOUR [PDF]
David W. Savage
openalex +1 more source
Hesperidin nanoparticles (HE NPs) effectively combat obesity and sleep‐disordered breathing in mice by enhancing leptin sensitivity. Through suppression of hypothalamic endoplasmic reticulum stress and restoration of leptin signaling, HE NPs promote weight loss and improve breathing during sleep.
Yixuan Wang+11 more
wiley +1 more source
This study identified that STK33 may serve as a target of Bufalin, which induces the degradation of STK33 and inhibits the growth of TNBC. Furthermore, STK33 is highly expressed in TNBC and enhances TNBC cell proliferation by phosphorylating and stabilizing CCAR1.
Shilong Jiang+11 more
wiley +1 more source
TISSUE DISTRIBUTION OF α‐14C‐LABELLED ALKYLOXY α‐PHENYLETHYLAMINES IN RELATION TO ANALGESIC ACTIVITY [PDF]
J. B. Brierley, A McCoubrey
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This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun+15 more
wiley +1 more source
Formamidines with antinociceptive and antiinflammatory activities [PDF]
Pursuing our investigations on 7-amino-2,3-polymethyleneindole derivatives, a set of 7-(dimethylaminomethylene)-amino-2,3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic ...
Boatto, Gianpiero+6 more
core
Trends in Opioid Analgesic-Prescribing Rates by Specialty, U.S., 2007-2012.
Benjamin Levy+3 more
semanticscholar +1 more source
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni+14 more
wiley +1 more source
Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck+7 more
wiley +1 more source