Results 141 to 150 of about 138,045 (265)

Searching for Mechanisms of Analgesic Activity in the Group of 1<i>H</i>-Pyrrolo[3,4-<i>c</i>]pyridine-1,3(2<i>H</i>)-dione Derivatives-In Vitro and In Vivo Studies. [PDF]

Methods Protoc
Dziubina A, Szkatuła D, Szafarz M, Siwek A, Kowalski M, Gdula-Argasińska J.   +5 more
europepmc   +1 more source

Intratendinous Porcine‐Derived Type I Collagen Injections Result in Clinical and Radiographic Improvement of Rotator Cuff Tendinopathy 1 Year After Treatment

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the clinical and radiological effectiveness of porcine‐derived type I collagen injections in patients with symptomatic rotator cuff tendinopathy. Methods In this monocentric pilot study conducted between 2022 and 2025, adults with clinically and radiologically confirmed rotator cuff tendinopathy received 3 ultrasound‐guided ...
Pietro Simone Randelli, Antonio Muzio, Carlo Stoppani, Chiara Fossati, Mauro Battista Gallazzi, Alessandra Menon   +5 more
wiley   +1 more source

Study of the Analgesic Activity of the Aqueous and Methanolic Extracts of Fresh Rhizome of Zingiber officinale in Wistar Rats. [PDF]

Cureus
Pakale DPV, Khanwelkar C, Thorat V, Jadhav S, Tiwari DD.   +4 more
europepmc   +1 more source

The Spanish Version of the Western Ontario Meniscal Evaluation Tool Is a Reliable, Valid, Precise, and Highly Responsive Instrument for Patients With Meniscal Pathology at a Minimum 6‐Month Follow‐Up

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To translate, culturally adapt, and validate the Western Ontario Meniscal Evaluation Tool (WOMET) into Peninsular Spanish and to evaluate its psychometric properties (reliability, validity, precision, and responsiveness) in patients undergoing knee arthroscopy for meniscal pathology. Methods This retrospective study with prospectively collected
Miguel Angel Palacios‐Flores, Maximiliano Ibañez, Zichun Liu Wang, Nicola Pizza, Raul Torres‐Claramunt, Simone Perelli, Joan Carles Monllau   +6 more
wiley   +1 more source

Pharmacokinetics and Quantitative Structure-Pharmacokinetics Relationship Study of Xanthine Derivatives with Antidepressant, Anti-Inflammatory, and Analgesic Activity in Rats. [PDF]

Pharmaceutics
Świerczek A, Szafarz M, Cios A, Kobierski J, Pociecha K, Attard Saliba D, Chłoń-Rzepa G, Wyska E.   +7 more
europepmc   +1 more source

Statistically Fragile Evidence Underlies Comparative Trials of Arthroscopic Meniscectomy Versus Nonoperative Management for Degenerative Meniscus Tears

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To assess the statistical robustness of comparative studies and randomized controlled trials (RCTs) comparing arthroscopic meniscal debridement or meniscectomy with nonoperative or sham interventions. Methods Comparative studies and RCTs of meniscus debridement or meniscectomy versus nonoperative or sham interventions were identified through a ...
Alexa P. Bosco, Rhea D. Rasquinha, Evan Voyer, Ashley E. Rosenberg, Matthew Quinn, Stephen Marcaccio   +5 more
wiley   +1 more source

Identification and analgesic activity study of analgesic protein Ⅶ-2 from Naja naja atra venom. [PDF]

J Venom Anim Toxins Incl Trop Dis
Sun Y, Zhang GB, Li S, Liu XY, Chen L, Bao PJ.   +5 more
europepmc   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Mutagenesis of the Peptide Inhibitor of ASIC3 Channel Introduces Binding to Thumb Domain of ASIC1a but Reduces Analgesic Activity. [PDF]

Mar Drugs
Khasanov TA, Maleeva EE, Koshelev SG, Palikov VA, Palikova YA, Dyachenko IA, Kozlov SA, Andreev YA, Osmakov DI.   +8 more
europepmc   +1 more source

Early Synovial Regulatory T Cell Engagement in Posttraumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early postinjury biologic processes within the synovium shape disease trajectories. We investigated whether synovial Treg cells are engaged during the early phase following joint injury and whether experimental enrichment of this ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source