Results 121 to 130 of about 225,759 (311)

ACUTE TOXICITY AND ANALGESIC ACTIVITY OF CRUDE FLAVONOIDS OF ACHILLEA WILHELMSII AND TEUCRIUM STOCKSIANUM

Khyber Medical University Journal, 2016
OBJECTIVES: To isolate total flavonoids from Achillea Wilhelmsii and Teucrium Stocksianum and screen them for possible analgesic activity and to determine the safe dose range of total flavonoids for preclinical studies in mice.
Niaz Ali, Ulfat Sultana, Syed Wadood Ali Shah, Muhammad Nabi, Shakir Ullah, Ismail Shah, Ghayour Ahmad   +6 more
doaj  

Preliminary assessment of the anti-inflammatory and analgesic effects of methanol leaf extract of Cussonia barteri (Araliaceae) in rodents

Herba Polonica, 2019
Introduction: Potato (Solanum tuberosum L.) is an important vegetable crop in Syria. Potato tuber moth Cussonia barteri is a small tree that grows in the sub-Saharan part of Africa.
Igbe Ighodaro, Edosuyi Osaze, Okhuarobo Agbonlahor, Pongri Adarki, Maduako Nkechi, Ehimen Isaac   +5 more
doaj   +1 more source

Analgesic Activity of 5-Acetamido-2-Hydroxy Benzoic Acid Derivatives and an In-Vivo and In-Silico Analysis of Their Target Interactions. [PDF]

Pharmaceuticals (Basel), 2023
Santos CBR, Lobato CC, Ota SSB, Silva RC, Bittencourt RCVS, Freitas JJS, Ferreira EFB, Ferreira MB, Silva RC, De Lima AB, Campos JM, Borges RS, Bittencourt JAHM.   +12 more
europepmc   +1 more source

Analgesic Activity of Morphine Suppository in Rats

YAKUGAKU ZASSHI, 1990
Analgesic activity of morphine administered rectally as a suppository was investigated in rats in order to ascertain analgesic activity of morphine suppository. Morphine hydrochloride given rectally as a suppository produced analgesic activity in a dose-related manner in the tail pressure and acetic acid-induced writhing tests, and its potency (ED50 ...
A, Kita, H, Nakamura, T, Kadokawa, T, Tan   +3 more
openaire   +3 more sources

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

Anti-Inflammatory and Analgesic Activity of Methanolic Root Extract of Verbascum sinaiticum Benth. [PDF]

J Inflamm Res, 2022
Asefa M, Teshome N, Degu A.
europepmc   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

N-Acetylcysteine Antagonizes NGF Activation of TrkA through Disulfide Bridge Interaction, an Effect Which May Contribute to Its Analgesic Activity. [PDF]

Int J Mol Sci, 2023
Govoni S, Fantucci P, Marchesi N, Vertemara J, Pascale A, Allegri M, Calvillo L, Vanoli E.   +7 more
europepmc   +1 more source

Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration

Advanced Science, EarlyView.
Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li, Hao Zhang, Lingtong Sun, Yingfeng Su, Yang Xu, Jian Huang, Jingchao Wen, Jinjin Zhu, Jianjun Ma, Wenbin Xu   +9 more
wiley   +1 more source

Study of the dermal anti-inflammatory, antioxidant, and analgesic activity of pinostrobin. [PDF]

Heliyon, 2022
González AS, Soto Tellini VH, Benjumea Gutiérrez DM.   +2 more
europepmc   +1 more source