Results 201 to 210 of about 10,975 (239)
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1997
Abstract As well as opsonization and cytolysis by C3 degradation products and the membrane attack complex, the activation of the complement system results in the generation of the proinflammatory polypeptides C3a, C4a, C5a, and C5adesArg, which are collectively described as anaphylatoxins or anaphylatoxic peptides (AT peptides).
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Abstract As well as opsonization and cytolysis by C3 degradation products and the membrane attack complex, the activation of the complement system results in the generation of the proinflammatory polypeptides C3a, C4a, C5a, and C5adesArg, which are collectively described as anaphylatoxins or anaphylatoxic peptides (AT peptides).
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Effects of the anaphylatoxins on circulation
Immunopharmacology, 1987Anaphylatoxins (e.g. activation fragments C3a, C4a and C5a) are bioactive cleavage products released from plasma components C3, C4 and C5, respectively, during complement activation. The biologic role of anaphylatoxins is generally characterized as pro-inflammatory, since these factors recruit numerous tissue mediators of the host defense system.
F, Marceau, C, Lundberg, T E, Hugli
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Biochemistry and Biology of Anaphylatoxins
Complement, 1986The molecular architecture of anaphylatoxins has been explored on several levels. Primary, secondary and tertiary structural parameters that dictate function of the C3a, C4a and C5a molecules are being elucidated with the aid of comparative sequence analyses, physical measurements and organic syntheses.
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Formation of anaphylatoxin in human serum
Experientia, 1969Es ist moglich, auch in menschlichem Serum eine Anaphylatoxinbildung (AT) durch Kontaktaktivierung oder Kobragift zu induzieren. Wegen der geringen Mengen, die entstehen, muss das wirksame Prinzip vor dem biologischen Nachweis angereichert werden. Menschliches AT verhalt sich in allen untersuchten Eigenschaften wie AT aus anderen Plasmaarten.
W, Vogt +3 more
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Anaphylatoxin Formation in Extracorporeal Circuits
Complement, 1986Anaphylatoxin radioimmunoassay techniques have been employed to define both the temporal profile and the amount of complement activation taking place in two different types of extracorporeal circuits. Prospective studies of patients undergoing both maintenance hemodialysis and cardiopulmonary bypass provided essentially similar findings. In both cases,
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Anaphylatoxins: Possible Roles in Disease
Complement, 1986Anaphylatoxins, in particular C3a and C5a, have various biological activities which suggest a role as mediators of inflammatory reactions: they cause contraction of smooth muscle, histamine release, increase in capillary permeability, adhesion of leukocytes to vascular endothelium, leukocyte chemotaxis, and aggregation of platelets and leukocytes. Most
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Regulation and function of anaphylatoxins and their receptors in allergic asthma.
Molecular Immunology, 2017Y. Laumonnier +3 more
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