Results 1 to 10 of about 35,071 (223)

Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters [PDF]

Emerging Infectious Diseases, 2023
Several occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor ...
Silke A. Riesle-Sbarbaro, Norman Kirchoff, Katharina Hansen-Kant, Alice Stern, Andreas Kurth, Joseph B. Prescott   +5 more
doaj   +2 more sources

Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters [PDF]

Emerging Infectious Diseases, 2021
Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available.
Brandi N. Williamson, Joseph Prescott, Jose L. Garrido, Raymond A. Alvarez, Heinz Feldmann, Maria I. Barría   +5 more
doaj   +2 more sources

Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 [PDF]

Emerging Infectious Diseases, 2020
Andes virus is unique among hantaviruses because it can be transmitted from person to person. This mechanism was previously supported by epidemiologic data and genetic evidence based only on partial sequences.
Daniel O. Alonso, Unai Pérez-Sautu, Carla M. Bellomo, Karla Prieto, Ayelén Iglesias, Rocío Coelho, Natalia Periolo, Isabel Domenech, Gabriel Talmon, Romina Hansen, Gustavo Palacios, Valeria P. Martinez   +11 more
doaj   +2 more sources

Mother-to-Child Transmission of Andes Virus through Breast Milk, Chile [PDF]

Emerging Infectious Diseases, 2020
Andes virus (ANDV) is the only hantavirus transmitted between humans through close contact. We detected the genome and proteins of ANDV in breast milk cells from an infected mother in Chile who transmitted the virus to her child, suggesting ...
Marcela Ferrés, Constanza Martínez-Valdebenito, Jenniffer Angulo, Carolina Henríquez, Jorge Vera-Otárola, María José Vergara, Javier Pérez, Jorge Fernández, Viviana Sotomayor, María Francisca Valdés, Diego González-Candia, Nicole D. Tischler, Cecilia Vial, Pablo Vial, Gregory Mertz, Nicole Le Corre   +15 more
doaj   +2 more sources

Presence and Persistence of Andes Virus RNA in Human Semen [PDF]

Viruses, 2023
When infecting humans, Andes orthohantavirus (ANDV) may cause a severe disease called hantavirus cardiopulmonary syndrome (HCPS). Following non-specific symptoms, the infection may progress to a syndrome of hemorrhagic fever combined with hyper-acute ...
Roland Züst, Rahel Ackermann-Gäumann, Nicole Liechti, Denise Siegrist, Sarah Ryter, Jasmine Portmann, Nicole Lenz, Christian Beuret, Roger Koller, Cornelia Staehelin, Andrea B. Kuenzli, Jonas Marschall, Sylvia Rothenberger, Olivier Engler   +13 more
doaj   +2 more sources

Virological characterization of a new isolated strain of Andes virus involved in the recent person-to-person transmission outbreak reported in Argentina. [PDF]

PLoS Neglected Tropical Diseases
On November 2, 2018, a person-to-person transmission outbreak of Andes virus (Orthohantavirus andesense) began in the small town of Epuyén, Argentina. The strain demonstrated a high capacity for sustained transmission among the human population requiring
Rocio Coelho, Sebastian Kehl, Natalia Periolo, Emiliano Biondo, Daniel Alonso, Celeste Perez, Darío Fernández Do Porto, Gustavo Palacios, Alexis Edelstein, Carla Bellomo, Valeria Paula Martinez   +10 more
doaj   +2 more sources

Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis [PDF]

Biological Research, 2003
We report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%.
NICOLE D TISCHLER, JORGE FERNÁNDEZ, ILSE MÜLLER, RODRIGO MARTÍNEZ, HÉCTOR GALENO, ELIECER VILLAGRA, JUDITH MORA, EUGENIO RAMÍREZ, MARIO ROSEMBLATT, PABLO D.T. VALENZUELA   +9 more
doaj   +4 more sources

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model [PDF]

mBio, 2020
Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer   +10 more
doaj   +2 more sources

New Andes virus isolate haplotype obtained during prospective close contacts follow-up of an Hantavirus cardiopulmonary syndrome fatal case, Chile [PDF]

Current Research in Microbial Sciences
Andes virus (ANDV) is a zoonotic orthohantavirus that causes hantavirus cardiopulmonary syndrome. Transmission occurs mainly through contact with infected rodent excreta and, less frequently, between humans. Viral isolation from human samples is rare; in
Aldo Barrera, Hade Ramos, Eugenia Fuentes-Luppichini, Constanza Martínez-Valdebenito, Javiera Pradenas, Catalina Rogers, Carlos Palma, Claudia Campillo, Maritza Navarrete, Nicole Le Corre, Jenniffer Angulo, Marcela Ferrés   +11 more
doaj   +2 more sources

Gastrointestinal Tract As Entry Route for Hantavirus Infection [PDF]

Frontiers in Microbiology, 2017
Background: Hantaviruses are zoonotic agents that cause hemorrhagic fevers and are thought to be transmitted to humans by exposure to aerosolized excreta of infected rodents. Puumala virus (PUUV) is the predominant endemic hantavirus in Europe.
Peter T. Witkowski, Casey C. Perley, Rebecca L. Brocato, Jay W. Hooper, Christian Jürgensen, Jörg-Dieter Schulzke, Detlev H. Krüger, Roland Bücker   +7 more
doaj   +4 more sources