Results 11 to 20 of about 35,071 (223)

Small interfering RNA inhibition of Andes virus replication. [PDF]

open access: yesPLoS ONE, 2014
Andes virus (ANDV) is the most common causative agent of hantavirus pulmonary syndrome (HPS) in the Americas, and is the only hantavirus associated with human-to-human transmission. Case fatality rates of ANDV-induced HPS are approximately 40%. There are
Cheng-Feng Chiang   +3 more
doaj   +2 more sources

Bivalent VSV Vectors Mediate Rapid and Potent Protection from Andes Virus Challenge in Hamsters [PDF]

open access: yesViruses
Orthohantaviruses may cause hemorrhagic fever with renal syndrome or hantavirus cardiopulmonary syndrome. Andes virus (ANDV) is the only orthohantavirus associated with human–human transmission. Therefore, emergency vaccination would be a valuable public
Joshua Marceau   +5 more
doaj   +2 more sources

Long-Term Single-Dose Efficacy of a Vesicular Stomatitis Virus-Based Andes Virus Vaccine in Syrian Hamsters [PDF]

open access: yesViruses, 2014
Andes virus (ANDV) is highly pathogenic in humans and is the primary etiologic agent of hantavirus cardiopulmonary syndrome (HCPS) in South America. Case-fatality rates are as high as 50% and there are no approved vaccines or specific therapies for ...
Joseph Prescott   +3 more
doaj   +2 more sources

Modeling the Immune Response for Pathogenic and Nonpathogenic Orthohantavirus Infections in Human Lung Microvasculature Endothelial Cells

open access: yesViruses, 2023
Hantaviruses, genus Orthohantavirus, family Hantaviridae, order Bunyavirales, are negative-sense, single-stranded, tri-segmented RNA viruses that persistently infect rodents, shrews, and moles. Of these, only certain virus species harbored by rodents are
Evan P. Williams   +6 more
doaj   +1 more source

BK Virus and Transplantation [PDF]

open access: yesViruses, 2021
As guest editors, we are pleased to present this Special Issue on BK virus (BKV) and transplantation with the intention of exploring some aspects related to BKV-associated diseases in transplant recipients, since they are still unclear [...]
Prezioso, Carla, Pietropaolo, Valeria
openaire   +4 more sources

A lethal disease model for New World hantaviruses using immunosuppressed Syrian hamsters. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
Hantavirus, the hemorrhagic causative agent of two clinical diseases, is found worldwide with variation in severity, incidence and mortality. The most lethal hantaviruses are found on the American continent where the most prevalent viruses like Andes ...
Valentijn Vergote   +6 more
doaj   +1 more source

Virus-Dependent Geographic Structure of Co-Circulating Viruses in a Single Bat Species. [PDF]

open access: yesMol Ecol
ABSTRACT Understanding the spatial spread of viruses within wildlife populations is often a key component of disease management efforts. Viral spread is likely constrained by host ecology, but inter‐virus differences in infection strategy might allow some viruses to overcome these constraints, leading to divergent population structures within a common ...
Holmes AL   +8 more
europepmc   +2 more sources

Junín Virus Pathogenesis and Virus Replication [PDF]

open access: yesViruses, 2012
Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina. Recently, significant progress has been achieved with the development of new technologies (e.g.
Olga Kolokoltsova   +6 more
openaire   +3 more sources

Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis [PDF]

open access: yes, 2020
Histoplasma capsulatum infection is a rare complication in the allogeneic stem cell transplant patients. Minimal guidance exists on how to appropriately manage histoplasmosis in these patients.
Agrawal, Vaibhav   +2 more
core   +1 more source

Hemodynamic and Pulmonary Permeability Characterization of Hantavirus Cardiopulmonary Syndrome by Transpulmonary Thermodilution

open access: yesViruses, 2019
Hantavirus cardiopulmonary syndrome (HCPS) is characterized by capillary leak, pulmonary edema (PE), and shock, which leads to death in up to 40% of patients.
René López   +6 more
doaj   +1 more source

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