Results 11 to 20 of about 348,703 (339)
Androgen regulation of the androgen receptor coregulators [PDF]
BMC Cancer, 2008 Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
openaire +5 more sources
Androgens and the breast [PDF]
Breast Cancer Research, 2009 Androgens have important physiological effects in women while at the same time they may be implicated in breast cancer pathologies. However, data on the effects of androgens on mammary epithelial proliferation and/or breast cancer incidence are not in full agreement.
Carolyn A. Bondy +2 more
openaire +3 more sources
Firing patterns of gonadotropin-releasing hormone neurons are sculpted by their biologic state [PDF]
Royal Society Open Science, 2020 Gonadotropin-releasing hormone (GnRH) neurons form the final pathway for the central neuronal control of fertility. GnRH is released in pulses that vary in frequency in females, helping drive hormonal changes of the reproductive cycle.
Jonathon Penix +4 more
doaj +1 more source
The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor [PDF]
, 2005 Prostate cancer is the second most common male malignancy in the western world an increasing incidence in an ageing population. Treatment of advanced prostate cancer relies on androgen deprivation.
Bakin RE +7 more
core +4 more sources
F1000Research, 2016 Prostate cancer is a leading cause of cancer-related death in Western men. Our understanding of the genetic alterations associated with disease predisposition, development, progression, and therapy response is rapidly improving, at least in part, owing ...
Angela C. Pine +3 more
doaj +1 more source
The Role of Testosterone in Menopause Management: A Review of Literature
Fertility & Reproduction, 2021 Background: Despite the lack of approved testosterone formulations for women in most countries, testosterone therapy is still being offered to women worldwide.
Eileen M. Manalo +2 more
doaj +1 more source
Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen. [PDF]
, 1993 Autoregulation is a control mechanism common to several proteins of the steroid/thyroid hormone receptor superfamily. In this work the effect of androgens and antiandrogens on the expression of the human androgen receptor (hAR) in prostate and breast ...
Blasschke, Dorothea +4 more
core +1 more source
Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells [PDF]
, 2013 The development and growth of prostate cancer is dependent on androgens; thus, the identification of androgen-regulated genes in prostate cancer cells is vital for defining the mechanisms of prostate cancer development and progression and developing new ...
Brinkmann +36 more
core +1 more source
Hedgehog Signalling in Androgen Independent Prostate Cancer [PDF]
, 2008 Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis.
Bisson, Isabelle +7 more
core +1 more source