WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics [PDF]
Prostate cancer cells with stem cell characteristics were identified in human prostate cancer cell lines by their ability to form from single cells self-renewing prostaspheres in non-adherent cultures.
A de la Taille+82 more
core +1 more source
Androgens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy [PDF]
Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy are strongly associated with bone loss and increased fracture risk.
Jia-Feng Chen+4 more
openaire +4 more sources
Androgens and Hypertension in Men and Women: a Unifying View. [PDF]
This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4.+4 more
core +1 more source
The impact of point mutations in the human androgen receptor : classification of mutations on the basis of transcriptional activity [PDF]
Peer reviewedPublisher ...
A Godoy+95 more
core +9 more sources
Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
A. Monteiro+63 more
core +2 more sources
Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus
Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng+6 more
doaj +1 more source
Role of imaging in the diagnosis and management of complete androgen insensitivity syndrome in adults [PDF]
Complete androgen insensitivity syndrome is an X-linked recessive androgen receptor disorder characterized by a female phenotype with an XY karyotype.
De Visschere, Pieter+4 more
core +4 more sources
Factors that influence the androgen receptor cistrome in benign and malignant prostate cells
The androgen receptor (AR) plays key roles in the development of prostate tissue and the development and progression of prostate cancer (PC). AR guides cytodifferentiation and homeostasis in benign luminal epithelial cells; however, in PC, AR instead ...
Ben T. Copeland+3 more
doaj +1 more source
Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]
Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Fittler, Friedrich+2 more
core +1 more source
Androgen-independent events in penile development in humans and animals. [PDF]
The common view on penile development is that it is androgen-dependent, based first and foremost on the fact that the genital tubercle forms a penis in males and a clitoris in females.
Baskin, Laurence+6 more
core +1 more source