Results 21 to 30 of about 346,728 (197)
Frontiers in Endocrinology, 2011 Brain aromatase is expressed only in the nerve cells of specific brain regions with a transient peak at the neonatal period when sexual behaviors become organized. Aromatase knockout (ArKO) mouse, generated to give light on the physiological functions of
Nobuhiro eHarada +2 more
doaj +1 more source
Role of Androgen Receptor in Prostate Cancer: A Review
The World Journal of Men's Health, 2018 Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain.
K. Fujita, N. Nonomura
semanticscholar +1 more source
Androgen-Induced Immunosuppression
Frontiers in Immunology, 2018 In addition to determining biological sex, sex hormones are known to influence health and disease via regulation of immune cell activities and modulation of target-organ susceptibility to immune-mediated damage.
M. G. Gubbels Bupp, T. Jorgensen
semanticscholar +1 more source
Mitogen Activated Protein kinase signal transduction pathways in the prostate
Cell Communication and Signaling, 2004 The biochemistry of the mitogen activated protein kinases ERK, JNK, and p38 have been studied in prostate physiology in an attempt to elucidate novel mechanisms and pathways for the treatment of prostatic disease.
Koul Sweaty +3 more
doaj +1 more source
The Role of Testosterone in Menopause Management: A Review of Literature
Fertility & Reproduction, 2021 Background: Despite the lack of approved testosterone formulations for women in most countries, testosterone therapy is still being offered to women worldwide.
Eileen M. Manalo +2 more
doaj +1 more source
Parasite-Mediated Mate Preferences in a Cooperatively Breeding Rodent
Frontiers in Ecology and Evolution, 2022 Females of many species discriminate among males when choosing a mate and this can bear indirect and direct benefits including the avoidance of parasite transmission from infested males.
Heike Lutermann +2 more
doaj +1 more source
Communications Biology, 2018 The androgen receptor is a major driver of prostate cancer and inhibition of its transcriptional activity using competitive antagonists, such as enzalutamide remains a frontline therapy for prostate cancer management.
J. Salami +10 more
semanticscholar +1 more source
The gut microbiota is a major regulator of androgen metabolism in intestinal contents
American Journal of Physiology. Endocrinology and Metabolism, 2019 Androgens exert important effects both in androgen-responsive tissues and in the intestinal tract. To determine the impact of the gut microbiota (GM) on intestinal androgen metabolism, we measured unconjugated (free) and glucuronidated androgen levels in
Hannah Colldén +10 more
semanticscholar +1 more source
Updates on androgen replacement therapy and lower urinary tract symptoms: a narrative review
The Aging Male, 2022 Lower urinary tract symptoms (LUTS) are caused by higher tension at the bladder neck level (due to fibrosis or stiffness) or benign prostatic hyperplasia, which causes static obstruction of the bladder outlet. Both forms cause a group of symptoms such as
Raed M. Al-Zoubi +6 more
doaj +1 more source
Reproductive Medicine and Biology, 2019 Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder among women of reproductive age and a major cause of infertility; however, the pathophysiology of this syndrome is not fully understood.
Satoko Osuka +6 more
doaj +1 more source