Results 21 to 30 of about 169,598 (149)
Frontiers in PhysiologyAtherosclerosis (AS), the leading cause of cardiovascular morbidity and mortality worldwide, exhibits significant sex differences in its incidence and pathological progression, yet the underlying molecular mechanisms remain fully elucidated. Ferroptosis,
Keying Yu +13 more
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Androgen regulation of the androgen receptor coregulators [PDF]
BMC Cancer, 2008 Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
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Frontiers in Reproductive HealthIntroductionAdolescence is a critical period of hormonal changes that affect growth, development, and behaviour. Estrogen, progesterone, and androgen are sex hormones that play important roles in reproductive development and functions.
Eric Kyei-Baafour +8 more
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MedComm, 2023 Aged male patients are more vulnerable to severe or critical symptoms of COVID‐19, but the underlying mechanism remains elusive. In this study, we analyzed previously published scRNA‐seq data from a large cohort of COVID‐19 patients, castrated and ...
Yinchuan Li +11 more
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Parasite-Mediated Mate Preferences in a Cooperatively Breeding Rodent
Frontiers in Ecology and Evolution, 2022 Females of many species discriminate among males when choosing a mate and this can bear indirect and direct benefits including the avoidance of parasite transmission from infested males.
Heike Lutermann +2 more
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Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?
Frontiers in Oncology, 2018 The PTEN gene encodes for the phosphatase and tensin homolog; it is a tumor suppressor gene that is among the most frequently inactivated genes throughout the human cancer spectrum. The most recent sequencing approaches have allowed the identification of
Raghavendra Tejo Karthik Poluri +2 more
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Sex Hormones Regulate Innate Immune Cells and Promote Sex Differences in Respiratory Virus Infection
Frontiers in Immunology, 2018 Sex differences in the incidence and severity of respiratory virus infection are widely documented in humans and murine models and correlate with sex biases in numbers and/or functional responses of innate immune cells in homeostasis and lung infection ...
Sapana Kadel +3 more
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Membrane androgen receptors may mediate androgen reinforcement [PDF]
Psychoneuroendocrinology, 2010 Anabolic-androgenic steroid (AAS) abuse is widespread. Moreover, AAS are reinforcing, as shown by self-administration in rodents. However, the receptors that transduce the reinforcing effects of AAS are unclear. AAS may bind to classical nuclear androgen receptors (ARs) or membrane receptors. We used two approaches to examine the role of nuclear ARs in
Satoru M, Sato +3 more
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Frontiers in Endocrinology, 2018 Nonsyndromic cryptorchidism is a common multifactorial, condition with long-term risks of subfertility and testicular cancer. Revealing the causes of cryptorchidism will likely improve prediction and prevention of adverse outcomes.
Julia S. Barthold, Richard Ivell
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The Role of Testosterone in Menopause Management: A Review of Literature
Fertility & Reproduction, 2021 Background: Despite the lack of approved testosterone formulations for women in most countries, testosterone therapy is still being offered to women worldwide.
Eileen M. Manalo +2 more
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