Results 71 to 80 of about 190,106 (204)

Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes [PDF]

open access: yes, 2014
Communication between organs and tissues is predominately controlled by hormones. Hormones regulate a vast variety of physiological and behavioural activities, including metabolism, growth and development, reproduction, sleep and mood.
Fürstenberger, Cornelia
core   +1 more source

Targeting NF-kappa B Signaling by Artesunate Restores Sensitivity of Castrate-Resistant Prostate Cancer Cells to Antiandrogens

open access: yesNeoplasia: An International Journal for Oncology Research, 2017
Androgen deprivation therapy (ADT) is the most preferred treatment for men with metastatic prostate cancer (PCa). However, the disease eventually progresses and develops resistance to ADT in majority of the patients, leading to the emergence of ...
Jessica J. Nunes   +4 more
doaj   +1 more source

Perioperative uses of histamine antagonists [PDF]

open access: yes, 1990
Histamine release and adverse pseudoallergic/allergic reactions during the perioperative period occur frequently. The incidence of such reactions is 20%-30% for all grades of severity, 1%-5% for systemic reactions, and 0.1%-0.5% for life-threatening ...
Lorenz, Wilfried   +3 more
core   +1 more source

Method of treatment for prostate cancer with androgen receptor antagonists and glucocorticoid receptor antagonists [PDF]

open access: yes, 2023
Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists.

core  

Hormonal status in patients with advanced prostatic cancer on the therapy with androgen blockade [PDF]

open access: yesVojnosanitetski Pregled, 2011
Background/Aim. Hormone suppression therapy is used in men with advanced prostate cancer improving chances of longer survival. The aim of this study was to investigate the influence of androgen blockades on testosterone and luteinizing hormone (LH ...
Vojinov Saša   +4 more
doaj   +1 more source

Recovery of hormone sensitivity after salvage brachytherapy for hormone refractory localized prostate cancer

open access: yesInternational Brazilian Journal of Urology, 2010
PURPOSE: Recent work has demonstrated the return of hormone sensitivity after palliative chemotherapy in androgen independent prostate cancer. We wished to establish whether a similar phenomenon existed in patients with no exposure to chemotherapy ...
Dan Smith, P. Nick Plowman
doaj   +1 more source

The protein composition of exosomes released by prostate cancer cells is distinctly regulated by androgen receptor-antagonists and -agonist to stimulate growth of target cells

open access: yesCell Communication and Signaling
Background Prostate cancer (PCa) is a prevalent malignancy in men worldwide, ranking as the second leading cause of cancer-related death in Western countries. Various PCa hormone therapies, such as androgen receptor (AR)-antagonists or supraphysiological
Golnaz Atri Roozbahani   +4 more
doaj   +1 more source

Androgen-induced rhox homeobox genes modulate the expression of AR-regulated genes [PDF]

open access: yes, 2010
Rhox5, the founding member of the reproductive homeobox on the X chromosome (Rhox) gene cluster, encodes a homeodomain-containing transcription factor that is selectively expressed in Sertoli cells, where it promotes the survival of male germ cells ...
Hu, Z.Y.   +7 more
core   +1 more source

The combination of antagonists of LHRH with antagonists of GHRH improves inhibition of androgen sensitive MDA-PCa-2b and LuCaP-35 prostate cancers

open access: yes, 2007
Antagonists of growth hormone-releasing hormone (GHRH) could extend the duration of response of androgen sensitive prostate cancers to androgen deprivation.
Stangelberger, Anton   +8 more
core   +1 more source

Androgen action via testicular arteriole smooth muscle cells is important for leydig cell function, vasomotion and testicular fluid dynamics [PDF]

open access: yes, 2010
Regulation of blood flow through the testicular microvasculature by vasomotion is thought to be important for normal testis function as it regulates interstitial fluid (IF) dynamics which is an important intra-testicular transport medium.
Bergh, A.   +39 more
core   +1 more source

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