Results 71 to 80 of about 113,908 (219)

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

Amino-Acid-Derived Androgen Receptor Modulators. [PDF]

ACS Med Chem Lett
Semenya J, Picazo E.
europepmc   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Similar androgen receptor expression in male and female AML. [PDF]

Blood Adv
Prabhu KS, Qian F, Sarkar D, Zheng H, Paulson RF.   +4 more
europepmc   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Drugging the intrinsically disordered transactivation domain of androgen receptor. [PDF]

Signal Transduct Target Ther
Obst JK, Banuelos CA, Jian K, Tien AH, Shkrabak OA, Wang J, Mawji NR, Tam T, Vuckovic M, Williams DE, Rogalski JC, Yuan X, Strynadka NCJ, Andersen RJ, Sadar MD.   +14 more
europepmc   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

Journal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis, Kelly Galisteu‐Luiz, Gabriela Leite Pedroso, Gustavo Lopes Puls, Leticia Cassaro, Bruno Boaventura Vieira, Fábio Lourenço Romano, Erika Calvano Küchler, Christian Kirschneck, Daniela Silva Barroso de Oliveira, Maria Bernadete Sasso Stuani, Mirian Aiko Nakane Matsumoto   +11 more
wiley   +1 more source

An Update on the Role of Androgens and Androgen Receptor in Triple-Negative Breast Cancer. [PDF]

Cells
Cortes BC, Queiroga FL, Illera JC, Ramos SC.   +3 more
europepmc   +1 more source

Gingival inflammation and plaque accumulation affect therapeutic outcomes in patients with acne vulgaris

Journal of Periodontology, EarlyView.
Abstract Background We hypothesized that acne vulgaris (AV) and gingivitis were associated through systemic inflammatory mechanisms, sharing common etiological factors. This study aimed to identify the association between AV and gingivitis and to assess changes in acne severity in relation to changes in the plaque index (PI).
Ömer Faruk Okumuş, Mustafa Yazıcı, Alpdoğan Kantarci   +2 more
wiley   +1 more source

Testosterone and androgen receptor pathway modulation in sepsis: immunometabolic mechanisms and therapeutic implications - a scoping review. [PDF]

Front Endocrinol (Lausanne)
Szczupak M, Kobak J, Kreczko M, Wierzchowska J, Krupa-Nurcek S.   +4 more
europepmc   +1 more source