Results 71 to 80 of about 17,593 (256)

New therapeutic targets in the treatment of prostate cancer

Indian Journal of Urology, 2007
Androgen deprivation therapy has become the mainstay of the treatment of advanced prostate cancer, being used in every clinical setting of the disease, from neoadjuvant to metastatic disease.
Vivek Vijjan, Deepak Dubey
doaj   +1 more source

Significance of androgen receptor and its potential for anti-androgen/androgen receptor-antagonist therapy in ovarian cancers

PLOS One
Introduction Androgen promotes tumorigenesis in some cancers; however, androgen receptor (AR) is not commonly examined in ovarian cancers (OCs). In this study, we evaluated AR expression among different types of OCs and compared the results to estrogen and progesterone receptors (ER & PR).
Teresa H. Kim, Sanaz Memarzadeh, Saba Vahdatshariatpanahi, Nora Ostrzega, Yuna Kang, Neda A. Moatamed   +5 more
openaire   +3 more sources

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Comparison of combination therapy with tamsulosin and dutasteride or finasteride in patients with benign prostatic hyperplasia: a randomized clinical trial

African Journal of Urology
Background Based on our observations at the largest outpatient urology clinic in Iran, patients for whom finasteride is prescribed as a secondary drug to tamsulosin tend to experience earlier and more severe sexual side effects without any difference in ...
Abbas Basiri, Rasool Zare, Mazyar Zahir, Amir Hossein Kashi, Mahsa Zobeiry, Nasrin Borumandnia, Amir Reza Abedi, Shabnam Golshan   +7 more
doaj   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Intracranial Assessment of Androgen Receptor Antagonists in Mice Bearing Human Glioblastoma Implants. [PDF]

Int J Mol Sci, 2023
Zalcman N, Larush L, Ovadia H, Charbit H, Magdassi S, Lavon I.   +5 more
europepmc   +1 more source

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

The Androgen Receptor in Breast Cancer

Frontiers in Endocrinology, 2018
Breast cancer (BC) is a hormone-related tumor. Despite the progress in BC therapy, this disease still remains the most common cancer amongst women around the world. This is likely due to the amazing BC heterogeneity. Accumulating evidence suggests a role
Pia Giovannelli, Marzia Di Donato, Giovanni Galasso, Erika Di Zazzo, Antonio Bilancio, Antimo Migliaccio   +5 more
doaj   +1 more source

DeepAR: a novel deep learning-based hybrid framework for the interpretable prediction of androgen receptor antagonists. [PDF]

J Cheminform, 2023
Schaduangrat N, Anuwongcharoen N, Charoenkwan P, Shoombuatong W.   +3 more
europepmc   +1 more source