Results 1 to 10 of about 109,598 (309)

The role of androgens on experimental pain sensitivity: a systemic review and meta-analysis [PDF]

open access: yesPAIN Reports
. Animal studies have shown androgens, especially testosterone, may have an analgesic effect on nociceptive behavior. However, it is unclear if this effect is present in humans.
Elizabeth Wu-Chen   +6 more
doaj   +2 more sources

Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism

open access: yesFrontiers in Endocrinology, 2023
An increasing number of studies have reported that androgens and androgen receptors (AR) play important roles in the regulation of glucose and lipid metabolism.
Lijun Yin, Shuo Qi, Zhiqiang Zhu
doaj   +1 more source

The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction [PDF]

open access: yesIranian Biomedical Journal, 2020
Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like PKC are involved in memory deficiency.
Sara Amiri   +4 more
doaj   +3 more sources

The role of 11-oxygenated androgens in prostate cancer

open access: yesEndocrine Oncology, 2023
11-oxygenated androgens are a class of steroids capable of activating the androgen receptor (AR) at physiologically relevant concentrations. In view of the AR as a key driver of prostate cancer (PC), these steroids are potential drivers of disease and ...
Gido Snaterse   +2 more
doaj   +1 more source

Androgen and Androgen Receptors as Regulators of Monocyte and Macrophage Biology in the Healthy and Diseased Lung

open access: yesFrontiers in Immunology, 2020
Androgens, the predominant male sex hormones, drive the development and maintenance of male characteristics by binding to androgen receptor (AR). As androgens are systemically distributed throughout the whole organism, they affect many tissues and cell ...
Mireya Becerra-Diaz   +2 more
doaj   +1 more source

Circulating adrenal 11-oxygenated androgens are associated with clinical outcome in endometrial cancer

open access: yesFrontiers in Endocrinology, 2023
ContextRecent evidence support that androgens play an important role in the etiology of endometrial cancer (EC). Adrenal-derived 11-oxygenated androgens are highly potent agonists of the androgen receptor (AR), comparable to testosterone (T) and ...
Cylia Dahmani   +7 more
doaj   +1 more source

Association between prenatal androgens and cord blood androgens, a path analysis

open access: yesScientific Reports, 2023
To determine association paths between prenatal androgens and cord blood androgens. The concentrations of T, FT, DHT, DHEA and SHBG in prenatal venous blood and cord blood were measured in 342 pregnant women and their neonates.
Hui Xu   +9 more
doaj   +1 more source

Androgens, Endometriosis and Pain

open access: yesFrontiers in Reproductive Health, 2021
The intriguing relationship between androgens, endometriosis and chronic pain continues to unfold. Determining this relationship is of crucial importance to gynecologists managing people with these conditions, as common treatments dramatically alter her ...
Susan F. Evans   +5 more
doaj   +1 more source

Profiling of androgen response in rainbow trout pubertal testis: relevance to male gonad development and spermatogenesis. [PDF]

open access: yesPLoS ONE, 2013
The capacity of testicular somatic cells to promote and sustain germ cell differentiation is largely regulated by sexual steroids and notably androgens. In fish species the importance of androgens is emphasized by their ability to induce sex reversal of ...
Antoine D Rolland   +6 more
doaj   +1 more source

Androgens’ effects on cerebrovascular function in health and disease

open access: yesBiology of Sex Differences, 2020
Androgens affect the cerebral vasculature and may contribute to sex differences in cerebrovascular diseases. Men are at a greater risk for stroke and vascular contributions to cognitive impairment and dementia (VCID) compared to women throughout much of ...
Charly Abi-Ghanem   +2 more
doaj   +1 more source

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