Results 1 to 10 of about 238,876 (343)
Androgens and Androgen Receptor Actions on Bone Health and Disease: From Androgen Deficiency to Androgen Therapy [PDF]
Cells, 2019 Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy ...
Jia-Feng Chen +4 more
doaj +4 more sources
Frontiers in Endocrinology, 2023 An increasing number of studies have reported that androgens and androgen receptors (AR) play important roles in the regulation of glucose and lipid metabolism.
Lijun Yin, Shuo Qi, Zhiqiang Zhu
doaj +1 more source
The role of 11-oxygenated androgens in prostate cancer
Endocrine Oncology, 2023 11-oxygenated androgens are a class of steroids capable of activating the androgen receptor (AR) at physiologically relevant concentrations. In view of the AR as a key driver of prostate cancer (PC), these steroids are potential drivers of disease and ...
Gido Snaterse +2 more
doaj +1 more source
Androgen regulation of the androgen receptor coregulators [PDF]
BMC Cancer, 2008 Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
openaire +5 more sources
Frontiers in Immunology, 2020 Androgens, the predominant male sex hormones, drive the development and maintenance of male characteristics by binding to androgen receptor (AR). As androgens are systemically distributed throughout the whole organism, they affect many tissues and cell ...
Mireya Becerra-Diaz +2 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ContextRecent evidence support that androgens play an important role in the etiology of endometrial cancer (EC). Adrenal-derived 11-oxygenated androgens are highly potent agonists of the androgen receptor (AR), comparable to testosterone (T) and ...
Cylia Dahmani +7 more
doaj +1 more source
The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction [PDF]
Iranian Biomedical Journal, 2020 Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like PKC are involved in memory deficiency.
Sara Amiri +4 more
doaj +1 more source
Association between prenatal androgens and cord blood androgens, a path analysis
Scientific Reports, 2023 To determine association paths between prenatal androgens and cord blood androgens. The concentrations of T, FT, DHT, DHEA and SHBG in prenatal venous blood and cord blood were measured in 342 pregnant women and their neonates.
Hui Xu +9 more
doaj +1 more source
Androgens, Endometriosis and Pain
Frontiers in Reproductive Health, 2021 The intriguing relationship between androgens, endometriosis and chronic pain continues to unfold. Determining this relationship is of crucial importance to gynecologists managing people with these conditions, as common treatments dramatically alter her ...
Susan F. Evans +5 more
doaj +1 more source