Results 1 to 10 of about 290,821 (338)
Androgens’ effects on cerebrovascular function in health and disease
Biology of Sex Differences, 2020 Androgens affect the cerebral vasculature and may contribute to sex differences in cerebrovascular diseases. Men are at a greater risk for stroke and vascular contributions to cognitive impairment and dementia (VCID) compared to women throughout much of ...
Charly Abi-Ghanem +2 more
doaj +2 more sources
Genomic and non-genomic effects of androgens in the cardiovascular system: clinical implications [PDF]
Clinical science, 2017 The principle steroidal androgens are testosterone and its metabolite 5α-dihydrotestosterone (DHT), which is converted from testosterone by the enzyme 5α-reductase.
Ahmed, S. Faisal +4 more
core +2 more sources
Cells, 2019 Androgens are not only essential for bone development but for the maintenance of bone mass. Therefore, conditions with androgen deficiency, such as male hypogonadism, androgen-insensitive syndromes, and prostate cancer with androgen deprivation therapy ...
Jia-Feng Chen +4 more
doaj +2 more sources
The role of androgens on experimental pain sensitivity: a systemic review and meta-analysis [PDF]
PAIN Reports. Animal studies have shown androgens, especially testosterone, may have an analgesic effect on nociceptive behavior. However, it is unclear if this effect is present in humans.
Elizabeth Wu-Chen +6 more
doaj +2 more sources
Frontiers in Endocrinology, 2023 An increasing number of studies have reported that androgens and androgen receptors (AR) play important roles in the regulation of glucose and lipid metabolism.
Lijun Yin, Shuo Qi, Zhiqiang Zhu
doaj +1 more source
The role of 11-oxygenated androgens in prostate cancer
Endocrine Oncology, 2023 11-oxygenated androgens are a class of steroids capable of activating the androgen receptor (AR) at physiologically relevant concentrations. In view of the AR as a key driver of prostate cancer (PC), these steroids are potential drivers of disease and ...
Gido Snaterse +2 more
doaj +1 more source
Frontiers in Immunology, 2020 Androgens, the predominant male sex hormones, drive the development and maintenance of male characteristics by binding to androgen receptor (AR). As androgens are systemically distributed throughout the whole organism, they affect many tissues and cell ...
Mireya Becerra-Diaz +2 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ContextRecent evidence support that androgens play an important role in the etiology of endometrial cancer (EC). Adrenal-derived 11-oxygenated androgens are highly potent agonists of the androgen receptor (AR), comparable to testosterone (T) and ...
Cylia Dahmani +7 more
doaj +1 more source
Sex differences in COVID-19: the role of androgens in disease severity and progression
Endocrine, 2020 Throughout the SARS-CoV2 pandemic, multiple reports show higher percentages of hospitalization, morbidity, and mortality among men than women, indicating that men are more affected by COVID-19.
Mohamed S. A. Mohamed +2 more
semanticscholar +1 more source
Association between prenatal androgens and cord blood androgens, a path analysis
Scientific Reports, 2023 To determine association paths between prenatal androgens and cord blood androgens. The concentrations of T, FT, DHT, DHEA and SHBG in prenatal venous blood and cord blood were measured in 342 pregnant women and their neonates.
Hui Xu +9 more
doaj +1 more source