Results 61 to 70 of about 2,751 (216)
Syntheses and structural confirmation of stereoisomers and various isotopologues of tetrahydromethyltestosterone [PDF]
This is an overview of the syntheses and structural conformation of in-house synthesized compounds. These compounds belong to the group of sereoisomers of metabolites of anabolic androgenic steroids and have been used in different studies in our working ...
Maria Kristina, Parr, Steff, Jakob
core +1 more source
Molecular Oncology, Volume 19, Issue 11, Page 3035-3059, November 2025.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Polychlorinated Androstanes from the Burrowing Sponge Cliona nigricans [PDF]
Organic Letters, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
E. FATTORUSSO E. +7 more
openaire +3 more sources
Advanced Science, Volume 12, Issue 42, November 13, 2025.The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao +12 more
wiley +1 more source
Detection of a Single Microdose of Testosterone and Recombinant EPO in Healthy Volunteers
Drug Testing and Analysis, Volume 17, Issue 11, Page 2220-2227, November 2025.Exogenous T was detected with IRMS regardless of T/E elevation—high serum T indicative for IRMS. rhEPO was detected in urine for 72 h in ITP and CP, and Tasso showed less sensitivity than previous DBS devices tested. ABSTRACT Doping with testosterone (T) and erythropoietin (EPO) in low doses (micro‐doping) is a challenge to detect.
Carmel Heiland +5 more
wiley +1 more source
The FASEB Journal, Volume 39, Issue 19, 15 October 2025.The adiponectin produced by Paneth cells suppresses intestinal stem cell renewal and differentiation by signaling through adiponectin receptor 1. This inhibitory effect is counterbalanced by gut microbiota‐derived indole‐3‐acetic acid, which activates the pregnane X receptor to downregulate adiponectin expression, consequently enhancing intestinal stem
Hang Liu +5 more
wiley +1 more source
Drug Testing and Analysis, Volume 17, Issue 10, Page 1857-1864, October 2025.A survey of 200 sports supplements purchased online in Australia and analysed for WADA Prohibited Substances. Athlete education regarding the use of sports supplements remains a high priority as 35% of the products contained WADA Prohibited Substances. ABSTRACT Sports supplements are used extensively by people involved in competitive sports. However, a
Louise Barker +4 more
wiley +1 more source
3α,4β-Dihydroxy-5α-androstan-17-one
Acta Crystallographica Section C Crystal Structure Communications, 1998 The ring conformation of the title compound, 3α,4β-di-hydroxy-5a-androstan-17-one, C 19 H 30 O 3 , is similar to that of the 5β-epimer except for the trans A/B ring junction and the geometry of ring D, which adopts a slightly deformed 13,14-half-chair conformation instead of the more common 14α-envelope conformation.
L. C. R. Andrade +6 more
openaire +1 more source
Drug Testing and Analysis, Volume 17, Issue 10, Page 1985-1995, October 2025.The metabolism of bolasterone in liver microsomes and in urine samples of rats orally treated was evaluated due to no availability of its extensive metabolism studies. Its mono‐ and di‐hydroxylated metabolites were detected by GC‐EI‐MS/MS, and the fragmentation pathways of metabolites were suggested.
Anca Raluca Muresan +5 more
wiley +1 more source
iMeta, Volume 4, Issue 5, October 2025.Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang +12 more
wiley +1 more source