Results 91 to 100 of about 798 (134)

In vivo 4-androstene-3,17-dione and 4-androstene-3β,17β-diol supplementation in young men

European Journal of Applied Physiology, 2000
To determine if known androgenic hormone precursors for testosterone in the androgen pathway would be readily transformed to testosterone, eight male subjects [mean age 23.8 (SEM 3) years, bodymass 83.1 (SEM 8.7) kg, height 175.6 (SEM 8.5) cm] underwent a randomized, double-blind, cross-over, placebo-controlled oral treatment with 200 mg of 4 ...
Earnest, Conrad P., Olson, Mark A., Broeder, Craig E., Breuel, Kevin F., Beckham, Susan G.   +4 more
openaire   +3 more sources

Steroids, XL. 15‐(hydroxymethyl)androstene and ‐estratriene derivatives [PDF]

Liebigs Annalen der Chemie, 1988
Abstract15α‐Hydroxymethyl‐5‐androstene‐3β,16β,17β‐triol (5d) and 16β‐hydroxy‐15α‐(hydroxymethyl)estratriene derivatives 9 were prepared from the corresponding 15‐hydroxymethylene‐16‐ketones 3 and 4. The configurations of the chiral centers were determined by means of chemical transformations and on the basis of spectroscopic data.
Vincze Irén, Somlai Csaba, Schneider Gyula, Dombi György   +3 more
openaire   +1 more source

ChemInform Abstract: Hydroalkoxycarbonylation of Androstene Derivatives.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
S. TOEROES, B. HEIL, G. GALIK, Z. TUBA
openaire   +1 more source

Stimulation of Human Hematopoiesis: The Androstene Link.

Blood, 2006
Abstract 5-Androstene-3β, 17β-diol (AED) is a naturally occurring member of the androstene series of steroids. In models of chemotherapy and radiation-induced mylosuppression, AED expanded hematopoietic stem and progenitor cells (HSPC), decreased need for clinical support and increased survival.
James Frincke, Charles Dowding, Christopher Reading, Armando Garsd, Ajay Malik, Dwight R. Stickney, Jessie R. Groothuis   +6 more
openaire   +1 more source

Beta-Androstenes and Resistance to Viral and Bacterial Infections

Neuroimmunomodulation, 2009
This report illustrates that the β-androstenes are indeed able to upregulate the host immune response to a level that enables the host to resist lethal infection by viruses or bacteria. These agents consist of a subgroup of steroids, which also mediates a rapid recovery of hematopoietic precursor cells after whole-body lethal radiation injury. In vivo,
openaire   +2 more sources

Hydroformylation – amidocarbonylation of androstene and pregnene derivatives

Applied Organometallic Chemistry, 2002
AbstractAndrostene and pregnene derivatives were functionalized by amides with rhodium or binary rhodium–cobalt catalysts. Whereas the Rh–PPh3 catalyzed reaction results in the unsaturated amido‐methylidene derivatives, the rapid hydrogenation of these compounds takes place in the presence of a basic PR3 ligand.
Emese Nagy, Csilla Benedek, Bálint Heil, Szilárd Tőrös   +3 more
openaire   +1 more source

SYNTHESIS OF MODIFIED STEROIDS IN THE ANDROSTANE AND ANDROSTENE SERIES

Organic Preparations and Procedures International, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
openaire   +1 more source

The metabolism in man of (3H)-5alpha-16-androsten-3alpha-ol and of (3H)-5alpha-16-androsten-3-one.

Hormone research, 1978
The in vitro metabolism in man of two 16-androstene steroids, 5alpha-16-androsten-3-one and 5alpha-16-androsten-3alpha-ol, has been studied using 3H-labelled tracers. 4 healthy subjects (2 of each sex) were chosen, and each labelled steroid was administered, by a single injection, to 1 man and 1 woman.
A E, Kingsbury, B W, Brooksbank
openaire   +2 more sources

Aromatization of Δ-androstene-3,17-dione, 19-hydroxy-Δ4-androstene-3,17-dione, and 19-oxo-Δ-androstene-3,17-dione at a common catalytic site in human placental microsomes

Biochemistry, 1977
Estrogen is believed to be biosynthesized from androstenedione in placental microsomes by a multienzyme pathway in which 19-hydroxyandrostenedione and 19-oxoandrostenedione (or the hydrated form) are obligatory intermediates. However, both 19-hydroxyandrostenedione and 19-oxoandrostenedione competitively inhibited aromatization of androstenedione, and ...
William G. Kelly, Dianne Judd, Ann Stolee   +2 more
openaire   +2 more sources

Studies of 16-Androstenes in an Infant With Virilizing Adrenal Carcinoma

Archives of Pediatrics & Adolescent Medicine, 1979
An 18-month-old girl with virilization was found to have an encapsulated right adrenal carcinoma (2 x3 cm) with great variation in nuclear size, frequent mitoses, and possible blood vessel invasion. Preoperative urinary excretions of 17-ketosteroids, androsterone, etiocholanolone, dehydroepiandrosterone, testosterone, pregnanetriol, 3alpha-androstenol,
T, Gregory, L I, Gardner, D B, Gower, D C, Bicknell, M J, Barlow   +4 more
openaire   +2 more sources