Results 161 to 170 of about 205,200 (274)
Abstract Chronic red blood cell (RBC) transfusion sustains patients with diverse hematologic disorders, but repeated transfusion leads to iron overload and alloimmunization. Reducing transfusion burden requires identifying donor units that circulate more effectively after storage, yet determinants of this variability remain incompletely defined.
James C. Zimring +13 more
wiley +1 more source
Barnes Hospital Bulletin [PDF]
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1252/thumbnail ...
core +1 more source
ABSTRACT Background In Sub‐Saharan Africa, anemia is a significant public health issue, affecting individuals of all ages. While prevention efforts focus on infants, children, and pregnant women, adolescents are overlooked often, leading to ongoing challenges.
David Mawutor Donkor +8 more
wiley +1 more source
Measuring Peripheral Tissue DHA Turnover Using a Novel 13C Enrichment Technique
ABSTRACT Recently, through the use of compound‐specific isotope analysis (CSIA), our lab validated the utility of 13C enrichment (δ13C) of docosahexaenoic acid (DHA) by using a very high δ13C in a diet switch study by measuring brain, liver, and plasma DHA turnover and half‐lives via high‐precision gas chromatography combustion isotope ratio mass ...
Brinley J. Klievik +3 more
wiley +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
Exclusions affect representativeness of Alzheimer's disease trial participants
Abstract BACKGROUND This study assessed how medical exclusion criteria of a prevention Alzheimer's disease trial impact potential eligibility and sample characteristics. METHODS Medical exclusion criteria from the Anti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial were applied to N = 3695 participants from the population‐based Health
Miriam T. Ashford +6 more
wiley +1 more source
Humanized mice offer new insight into immune‐hormonal changes during menopause. Traditional models lack accuracy in replicating human menopause physiology. Functional foods may ease symptoms but need testing in human‐relevant systems. Combining humanized mice with diet research can improve women's health outcomes.
Nisansala Chandimali +6 more
wiley +1 more source
Abstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Giuseppe Grande +6 more
wiley +1 more source
Opposite to the age trend in healthy children, cerebral blood flow increases with age in children with sickle cell anaemia. Early treatment with hydroxyurea (hydroxycarbamide) may help slow this abnormal trend and protect brain functions.
Ping Zou Stinnett +10 more
wiley +1 more source

