Results 41 to 50 of about 404,902 (308)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Modern aspects in anesthesia of small laboratory animals

Южно-Российский онкологический журнал, 2022
Experiments with small laboratory animals are required for better understanding of a disease flow, for studying the mechanisms of it’s development and for the development of new therapeutic strategies.
S. V. Gurova, M. V. Mindar, D. V. Khodakova   +2 more
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Comparison of surgical field visibility during propofol or desflurane anesthesia for middle ear microsurgery

BMC Anesthesiology, 2019
Background To compare surgical field visibility between patients given propofol/remifentanil (PR) or desflurane/remifentanil (DR) anesthesia. Methods A total of 80 adult patients undergoing middle ear microsurgery due to cholesteatoma otitis media with ...
Xia Yuan, Tingjie Liu, Chunbo Hu, Xia Shen   +3 more
doaj   +1 more source

Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast

FEBS Open Bio, 2021
Although general anesthesia is indispensable during modern surgical procedures, the mechanism by which inhalation anesthetics act on the synaptic membrane at the molecular and cellular level is largely unknown.
Fumi Kozu, Kanae Shirahama‐Noda, Yasuhiro Araki, Shintaro Kira, Hitoshi Niwa, Takeshi Noda   +5 more
doaj   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Sedative Agents, Synthetic Torpor, and Long-Haul Space Travel—A Systematic Review

Life
Background: With renewed interest in long-duration space missions, there is growing exploration into synthetic torpor as a countermeasure to mitigate physiological stressors.
Thomas Cahill, Nataliya Matveychuk, Elena Hardiman, Howard Rosner, Deacon Farrell, Gary Hardiman   +5 more
doaj   +1 more source

Comparative Evaluation of Modern Inhalation Anesthetics in Carotid Endarterectomy

Общая реаниматология, 2019
The purpose of the study was to compare the possibility of rapid activation of elderly patients after carotid endarterectomy performed under sevoflurane- or desflurane-based anesthesia. Materials and methods.
V. A. Aliev, A. G. Yavorovskii, A. A. Shaposhnikov, I. Zh. Loriya, M. S. Vetsheva   +4 more
doaj   +1 more source

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

Advanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee, Byung Ik Park, Gihyeon Yim, Hyunjae Yoo, Sangjun Ma, Jundong Park, Jeong‐Yun Sun   +6 more
wiley   +1 more source

Inhalation anesthetics in a comprehensive enhanced recovery after surgery program

Клиническая практика, 2018
Over the recent years, an increasing attention has been paid in the Russian healthcare to the concept of afast-track surgery also known as enhanced recovery after surgery (ERAS).
N. V. Kutsevolova, Yu. E. Makhno, A. S. Anoshin, E. V. Lepikhov, M. A. Sanchenko, E. M. Dorofeeva, N. A. Moshenkova, A. E. Kuklenko, N. V. Naklonnaya   +8 more
doaj   +1 more source