Results 51 to 60 of about 356,347 (353)
Common anesthetic molecules prefer to partition in liquid disorder phase domain in a composite multicomponent membrane [PDF]
Phys. Rev. E 98, 012409 (2018), 2018 Despite a vast clinical application of anesthetics, the molecular level of understanding of general anesthesia is far from our reach. Using atomistic molecular dynamics simulation, we study the effects of common anesthetics: ethanol, chloroform and methanol in the fully hydrated symmetric multicomponent lipid bilayer membrane comprising of an ...
arxiv +1 more source
Modern aspects in anesthesia of small laboratory animals
Южно-Российский онкологический журнал, 2022 Experiments with small laboratory animals are required for better understanding of a disease flow, for studying the mechanisms of it’s development and for the development of new therapeutic strategies.
S. V. Gurova +2 more
doaj +1 more source
Liquid general anesthetics lower critical temperatures in plasma membrane vesicles [PDF]
, 2013 A large and diverse array of small hydrophobic molecules induce general anesthesia. Their efficacy as anesthetics has been shown to correlate both with their affinity for a hydrophobic environment and with their potency in inhibiting certain ligand gated ion channels.
arxiv +1 more source
CLINICAL AND ECONOMIC EVALUATION OF INHALATION ANESTHETICS USE
Вестник анестезиологии и реаниматологии, 2018 Sevoflurane is one of the widely used inhalation anesthetics as well as desflurane, which started to be used in Russia in 2012. These drugs possess similar properties; however, desflurane provides faster restoration of cognitive functions and reduces the
R. R. Gubaydullin +2 more
doaj +1 more source
Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast
FEBS Open Bio, 2021 Although general anesthesia is indispensable during modern surgical procedures, the mechanism by which inhalation anesthetics act on the synaptic membrane at the molecular and cellular level is largely unknown.
Fumi Kozu +5 more
doaj +1 more source
Membrane Nanodomains Homeostasis During Propofol Anesthesia as Function of Dosage and Temperature [PDF]
, 2020 Some anesthetics bind and potentiate gamma-aminobutyric-acid-type receptors, but no universal mechanism for general anesthesia is known. Furthermore, often encountered complications such as anesthesia induced amnesia are not understood. General anesthetics are hydrophobic molecules easily dissolving into lipid bilayers.
arxiv +1 more source
Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series [PDF]
, 2020 Ketamine administration in sub-dissociative doses in the emergency department (ED) results in effective pain relief in patients with acute traumatic and non-traumatic pain, chronic pain, and opioid-tolerant pain.
Butt, Mahlaqa +5 more
core
The Effects of Changing from Isoflurane to Desflurane on the Recovery Profile during the Latter Part of Anesthesia [PDF]
, 2010 It is not known whether changing from isoflurane to desflurane during the latter part of anesthesia shows early emergence and recovery in long surgery.
Baek, Chong-Wha +8 more
core +1 more source
PLoS ONE, 2022 IntroductionWith the widespread use of one-lung ventilation (OLV) in thoracic surgery, it is unclear whether maintenance anesthetics such as propofol and inhaled anesthetics are associated with postoperative complications.
Jing Yang +3 more
doaj +2 more sources
FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source