Results 71 to 80 of about 11,104 (303)
Advanced Science, EarlyView.An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan +10 more
wiley +1 more source
Effect of inhalation anesthetics on cerebral blood flow [PDF]
, 2017 Primarni cilj anestezije je održavanje fiziološke homeostaze. To zahtijeva monitoring i tretman kardiovaskularnih, respiratornih, neuroloških i bubrežnih funkcijskih promjena tokom perioperativnog perioda kako bi se minimizirali neželjeni ishodi ...
Marketin, Antonio
core
Synchronization‐Dissipation in the Cardiorespiratory System
Advanced Science, EarlyView.By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border +3 more
wiley +1 more source
Xenon and Other Volatile Anesthetics Change Domain Structure in Model Lipid Raft Membranes
, 2016 Inhalation anesthetics have been in clinical use for over 160 years, but the molecular mechanisms of action continue to be investigated. Direct interactions with ion channels received much attention after it was found that anesthetics do not change the ...
David L. Worcester (1317138) +1 more
core +1 more source
The effect of anesthetics on carotenoid pigmentation and behavior in Arctic char (Salvelinus alpinus) [PDF]
, 2015 Status of individual animals is often shown in pigmentation. For instance, stress responsiveness is associated with melanin-based pigmentation in vertebrates in general.
Nilsson, Jan +10 more
core +1 more source
Advanced Science, EarlyView.By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang +13 more
wiley +1 more source
CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
Hepatology, EarlyView., 2022 A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang +18 more
wiley +1 more source
Toxics, 2018 This study was undertaken to determine whether exposure of operating room personnel to inhalation anesthetics, nitrous oxide, isoflurane, and sevoflurane was associated with any hematological changes. This historical cohort study was performed in 2018 at
Fatemeh Amiri +4 more
doaj +1 more source
Effect of volatile anesthetics on BLI signal.
, 2012 The effect on photon emission (PE) of isoflurane (A), sevoflurane (B) and desflurane (C) anesthetics is expressed relative to control samples, containing 100% oxygen without inhalation anesthetic. Intact cells were used.
Tony Lahoutte (82410) +7 more
core +1 more source
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source