Results 81 to 90 of about 18,313 (287)

High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]

, 2018
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E., Dai, Jennifer B., Daigle, Renee, Forman, Stuart A., Halpin, Elizabeth S., Jounaidi, Youssef, Marte-Oquendo, Francisco, Porco, John A., Schaus, Scott E., Trilles, Richard, Xu, Wenqing, Yang, Xiaoxuan, Yu, Buwei   +12 more
core   +1 more source

Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex

Advanced Healthcare Materials, EarlyView.
Flexible, biocompatible PVDF nanofibers embedded with magnetite nanodiscs enable wireless magnetoelectric neuromodulation. Shape anisotropy of the nanodiscs facilitates magnetostrictive strain transfer under alternating magnetic fields, allowing activation of neurons in vitro and behavioral modulation in vivo, without requiring rigid implants or ...
Lorenzo Signorelli, Anouk Wolters, Vicente Durán Toro, Jonas Englhard, Mahdieh Shojaei Baghini, Elif Koçar, Franziska Wasner, Nadine I. Goldenstein, Hadi Heidari, Julien Bachmann, Sarah Hescham, Danijela Gregurec   +11 more
wiley   +1 more source

A Simple, Inexpensive, and Effective Light- Carrying Laryngoscopic Blade for Orotracheal Intubation of Rats [PDF]

, 2006
The research paradigm of using large laboratory animals, in which oroendotracheal intubations are relatively easy, is shifting toward the use of small animals, such as rodents, in which oropharyngeal access is limited, the arytenoid cartilage cycles are ...
Molthen, Robert C.
core   +1 more source

Como Funciona o Xénon: Mecanismos de Neuro e Cardioprotecção [PDF]

, 2014
INTRODUCTION: The Xenon, a noble gas, has anesthetics properties, associated with remarkable hemodynamic stability as well as cardioprotective, neuroprotective proprieties.
Andrade, L, Lourenço, A, Morais, R, Tavares, J   +3 more
core   +1 more source

A Hierarchically Structured, Stretchable, Anti‐Biofouling Encapsulation for Biodegradable Electronics

Advanced Healthcare Materials, EarlyView.
A soft, stretchable, anti‐biofouling encapsulant is developed by integrating organosilicon nanowire networks with microstructured biodegradable elastomers. The hierarchical surface exhibits superhydrophobicity and enhances water barrier properties by 420% over pristine polymers, while preserving mechanical integrity.
Won Bae Han, Sungkeun Han, Gwan‐Jin Ko, Ulziituya Batjargal, Wonjun Jang, Venkata Ramesh Naganaboina, Han‐Jun Kim, Suk‐Won Hwang   +7 more
wiley   +1 more source

Melting transitions in biomembranes

, 2019
We investigated melting transitions in biological membranes in their native state that include their membrane proteins. These membranes originated from \textit{E. coli}, \textit{B.
Heimburg, Thomas, Konrad, Manfred, Madsen, Soren B., Music, Tea, Pollakowski, Denis, Tounsi, Fatma   +5 more
core   +1 more source

The influence of anesthetics, neurotransmitters and antibiotics on the relaxation processes in lipid membranes [PDF]

, 2007
In the proximity of melting transitions of artificial and biological membranes fluctuations in enthalpy, area, volume and concentration are enhanced. This results in domain formation, changes of the elastic constants, changes in permeability and slowing ...
Antonov V. F., Antonov V. F., Blume A., Bovill J. G., Brown D. A., Böckmann R. A., Böttner M., Cannon B., Cantor R. S., Cantor R. S., Cantor R. S., Chapman D., Cruzeiro-Hansson L., Ebel H., Ebel H., Elamrani K., Franks N., Gaus K., Gennis R. B., Genz A., Grabitz P., Gruenewald B., Halstenberg S., Halstenberg S., Heimburg T., Heimburg T., Heimburg T., Heimburg T., Heimburg T., Helms J. B., Hill T. L., Hinderliter A., Hinz H.-J., Holzwarth J. F., Holzwarth J. F., Jackson M. B., Jacobson K., Johnson M. L., Kaufmann K., Kharakoz D. P., Korlach J., Krasowski M., Lee J., Melchior D. L., Melo E. C., Mitaku S., Mountcastle D., Nagle J. F., Onsager L., Onsager L., Papahadjopoulos D., Pollakowski D., Sackmann E., Salinas D. G., Schmidt D., Seeger H., Seeger H. M., Seeger H. M., Simons K., Singer S., Steim J. M., Strehlow U., Tamura K., Thompson T., Trudell J. R., Träuble H., Tsong T. Y., Tsong T. Y., Turnheim K., Ueda I., van Osdol W. W., van Osdol W. W., van Osdol W. W., van Osdol W. W., Vaz W. L., Winter R., Yao H.   +76 more
core   +2 more sources

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Sevoflurane Pre-conditioning Ameliorates Diabetic Myocardial Ischemia/Reperfusion Injury Via Differential Regulation of p38 and ERK. [PDF]

, 2020
Diabetes mellitus (DM) significantly increases myocardial ischemia/reperfusion (MI/R) injury. During DM, cardioprotection induced by conventional pre-conditioning (PreCon) is decreased due to impaired AMP-activated protein kinase (AMPK) signaling.
Cao, Jimin, Christopher, Theodore, Gao, Erhe, Guo, Rui, Jiao, Liyuan, Lau, Wayne Bond, Lopez, Bernard, Ma, Xin-Liang, Wang, Yajing, Xie, Dina, Zhang, Yanqing, Zhao, Jianli   +11 more
core   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source