Results 41 to 50 of about 636 (203)

Anesthetic Management of Labor in a Woman with Hereditary Angioedema

Acta Médica Portuguesa
N/a.
Inês P. Rodrigues, Maria M. Armindo, Luísa Marinho   +2 more
doaj   +1 more source

Impact of Chronic Urticaria on Major Life‐Changing Decisions: Greater Burden in Social, Physical, and Job/Career Domains

JEADV Clinical Practice, EarlyView.
The 32‐item Major Life‐Changing Decision Profile was validated and applied to 111 Turkish‐speaking chronic urticaria patients. Overall, 79.3% reported at least one affected major life‐changing decision, most commonly in social (69.4%), physical (56.8%) and job/career (36.9%) domains. Higher impact was observed in patients with disease onset ≤ 45 years (
Sinem Ornek Ozdemir, Kubra Cure, Defne Baskurt, Rabia Oztas Kara, Muhammed Burak Yucel, Esra Sarac, Pelin Kuteyla Can, Bahar Sevimli Dikicier, Ragip Ertas, Andac Salman, Murat Türk, Utkan Kızıltac, Faraz Mahmood Ali, Sam Salek, Andrew Y. Finlay, Emek Kocaturk   +15 more
wiley   +1 more source

Novel SERPING1 Genetic Variant in Two Family Members with Hereditary Angioedema

Acta Médica Portuguesa
Hereditary angioedema is a rare, autosomal dominant, genetic disorder characterized by recurrent episodes of angioedema. Over 800 SERPING1 gene variants have been reported, and their clinical profiles and causal genetic variants are highly heterogeneous.
Sofia Cosme Ferreira, Alexandra Rosa, Filipa Sousa, Alejandro Mendoza-Alvarez, Rafaela González-Montelongo, Ariel Callero, Carlos Flores, Rita Câmara   +7 more
doaj   +1 more source

Angioedema

World Allergy Organization Journal, 1984
Angioedema can be caused by either mast cell degranulation or activation of the kallikrein-kinin cascade. In the former case, angioedema can be caused by allergic reactions caused by immunoglobulin E (IgE)-mediated hypersensitivity to foods or drugs that can also result in acute urticaria or a more generalized anaphylactic reaction.
openaire   +4 more sources

A Scoping Review of Laryngeal Edema Rating Scales for Extubated Acute Respiratory Failure Survivors

The Laryngoscope, EarlyView.
This scoping review identified existing laryngeal edema rating scales and evaluated whether any are adequately designed for post‐extubation acute respiratory failure (ARF) survivors. Across 35 included studies, most used subjective binary classifications and only the RTOG and Patterson Edema scales had operational definitions and reliability/validity ...
Lalita Sabat, Winston Liu, Michael H. Ieong, Lauren F. Tracy, Gintas P. Krisciunas   +4 more
wiley   +1 more source

Histaminergic angioedema and chronic urticaria

, 2015
International audienceMost angioedemas are histaminergic and correspond to deep urticarial swelling. Recurrent histaminergic angioedema led to the diagnosis of chronic urticaria, even when there are no superficial associated hives. Chronic urticaria is a
Nosbaum, Audrey, Augey, Frédéric, Bérard, Frédéric, Goujon, Catherine, Hacard, Florence, Bensaid, Benoit, Nicolas, Jean-François   +6 more
core   +1 more source

Aspectos clínicos e diagnósticos, qualidade de vida, utilidade, adesão terapêutica e custos para angioedema hereditário associado à deficiência de C1-esterase

HU Revista
Introdução:  O angioedema hereditário associado à deficiência de C1 esterase (AEH-C1-INH) é uma doença rara (DR) que se manifesta com a ocorrência de episódios recorrentes de angioedema não pruriginoso subcutâneo ou submucoso, o que gera impactos em ...
Alex de Cerqueira Silveira Figueiredo, Angelina Xavier Acosta, Regis de Albuquerque Campos, Camila Ferreira Ramos, Temis Felix, Ney Boa-Sorte   +5 more
doaj   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Diagnostyka wrodzonego obrzęku naczynioruchowego [PDF]

, 2018
Hereditary angioedema (HAE) is a rare disorder characterized by acute episodes of edema formation in the subcutis and/or the submucosa. The clinical picture of the disease resembles that of histamine-mediated angioedema, nevertheless bradykinin release ...
Cervenak, László, Kőhalmi, Kinga Viktória, Farkas, Henriette   +2 more
core  

Berotralstat for long-term prophylaxis of hereditary angioedema in Japan: Parts 2 and 3 of the randomized APeX-J Phase III trial

World Allergy Organization Journal
Background: Berotralstat is a once-daily oral inhibitor of plasma kallikrein for the prophylaxis of hereditary angioedema (HAE) in patients ≥12 years. APeX-J aimed to evaluate the efficacy and safety of berotralstat in Japan.
Daisuke Honda, MD, PhD, Michihiro Hide, MD, PhD, Tomoo Fukuda, MD, PhD, Keisuke Koga, MD, PhD, Eishin Morita, MD, PhD, Shinichi Moriwaki, MD, Yoshihiro Sasaki, MD, PhD, Yusuke Suzuki, MD, PhD, Phil Collis, PhD, Douglas T. Johnston, DO, Dianne Tomita, MPH, Bhavisha Desai, PharmD, Isao Ohsawa, MD, PhD   +12 more
doaj   +1 more source