Results 11 to 20 of about 991,798 (411)
Frondoside A suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis [PDF]
, 2013 A major challenge for oncologists and pharmacologists is to develop less toxic drugs that will improve the survival of lung cancer patients. Frondoside A is a triterpenoid glycoside isolated from the sea cucumber, Cucumaria frondosa and was shown to be a
Adrian, Thomas E +8 more
core +6 more sources
Cold Spring Harbor Perspectives in Biology, 2011 Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult, angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement membrane, and vascular sprouting within interstitial matrix. During this sprouting phase, ECM binding to integrins provides critical signaling support for EC proliferation ...
Donald R, Senger, George E, Davis
openaire +2 more sources
Cancer cell survival depends on collagen uptake into tumor-associated stroma
Nature Communications, 2022 Collagen can be a metabolic source to fuel cancer growth. Here the authors show that cell surface protein TEM8 mediates the binding and uptake of collagen in stromal cells and these cells processed the collagen to glutamine, providing an alternative ...
Kuo-Sheng Hsu +21 more
doaj +1 more source
Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]
, 2012 The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J. +2 more
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Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis
Journal of Nanobiotechnology, 2021 Skin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life.
H. Nosrati +7 more
semanticscholar +1 more source
Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension [PDF]
, 2018 Right ventricular (RV) function is the primary prognostic factor for both morbidity and mortality in pulmonary hypertension (PH). RV hypertrophy is initially an adaptive physiological response to increased overload; however, with persistent and/or ...
Bonnet, Sébastien +3 more
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VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone
npj Regenerative Medicine, 2023 Vascular endothelial growth factor-A (VEGF) physiologically regulates both angiogenesis and osteogenesis, but its application in bone tissue engineering led to contradictory outcomes.
Andrea Grosso +8 more
doaj +1 more source
Science Advances, 2021 Sustained release of oxygen accelerates diabetic wound healing by regulating epithelialization, angiogenesis, and inflammation.
Ya Guan +7 more
semanticscholar +1 more source
Angiogenesis, 2010 Imaging of angiogenesis is an important tool in the diagnosis of disease. Small molecule or nanoparticular probes are currently developed to identify angiogenic endothelium with non-invasive imaging techniques such as magnetic resonance and ultrasound imaging. These techniques are very valuable since they would not only contribute to improved diagnosis,
Mulder, W.J.M., Griffioen, A.W.
openaire +4 more sources
The relationship between angiogenesis and cyclooxygenase-2 expression in prostate cancer [PDF]
, 2005 <b>OBJECTIVE</b>: To test the hypothesis that angiogenesis in prostate cancer is associated with tumour invasion and metastasis, and that this is mediated through increased cyclooxygenase-2 (COX-2) expression.
Bartlett, J.M.S. +3 more
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