Results 11 to 20 of about 952,689 (432)
Pathological angiogenesis: mechanisms and therapeutic strategies
Angiogenesis, 2023 In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-existing ones, is an essential process for growth and development. Different mechanisms such as vasculogenesis, sprouting, intussusceptive, and coalescent angiogenesis,
A. Dudley, A. Griffioen
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Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.
New England Journal of Medicine, 2020 BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease, relatively little is known about the associated morphologic ...
M. Ackermann +13 more
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Advances in Cancer Research, 2020 The hypothesis that tumors are angiogenesis dependent has, in the past decade, generated new investigations designed to elucidate the mechanism of angiogenesis itself. Many laboratories are now engaged in this pursuit. Some are studying angiogenesis that
Farah Fatmawati, Whendy Wijaksono
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Cold Spring Harbor Perspectives in Biology, 2011 Extracellular matrix (ECM) is essential for all stages of angiogenesis. In the adult, angiogenesis begins with endothelial cell (EC) activation, degradation of vascular basement membrane, and vascular sprouting within interstitial matrix. During this sprouting phase, ECM binding to integrins provides critical signaling support for EC proliferation ...
Donald R, Senger, George E, Davis
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VEGF dose controls the coupling of angiogenesis and osteogenesis in engineered bone
npj Regenerative Medicine, 2023 Vascular endothelial growth factor-A (VEGF) physiologically regulates both angiogenesis and osteogenesis, but its application in bone tissue engineering led to contradictory outcomes.
Andrea Grosso +8 more
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Hopf bifurcation of a free boundary problem modeling tumor growth with angiogenesis and two time delays [PDF]
, 2021 This paper concerns a free boundary problem modeling tumor growth with angiogenesis and two time delays. The two delays represent the time taken for cells to undergo mitosis and modify the rate of cell loss because of apoptosis, respectively. We study the stability of stationary solutions and find that Hopf bifurcation occurs under some conditions ...
arxiv +1 more source
Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited [PDF]
, 2012 The cellular and molecular mechanisms of tumor angiogenesis and its prospects for anti-angiogenic cancer therapy are major issues in almost all current concepts of both cancer biology and targeted cancer therapy. Currently, (1) sprouting angiogenesis, (2)
Dumont, Daniel J. +2 more
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Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis
Journal of Nanobiotechnology, 2021 Skin is the body’s first barrier against external pathogens that maintains the homeostasis of the body. Any serious damage to the skin could have an impact on human health and quality of life.
H. Nosrati +7 more
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Cancer cell survival depends on collagen uptake into tumor-associated stroma
Nature Communications, 2022 Collagen can be a metabolic source to fuel cancer growth. Here the authors show that cell surface protein TEM8 mediates the binding and uptake of collagen in stromal cells and these cells processed the collagen to glutamine, providing an alternative ...
Kuo-Sheng Hsu +21 more
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Science Advances, 2021 Sustained release of oxygen accelerates diabetic wound healing by regulating epithelialization, angiogenesis, and inflammation.
Ya Guan +7 more
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