Results 41 to 50 of about 182,387 (331)

Development of a one-step embryonic stem cell-based assay for the screening of sprouting angiogenesis

open access: yesBMC Biotechnology, 2007
Background Angiogenesis assays are important tools for the identification of regulatory molecules and the potential development of therapeutic strategies to modulate neovascularization.
Desroches-Castan Agnès   +5 more
doaj   +1 more source

The statistical theory of the angiogenesis equations [PDF]

open access: yesarXiv, 2022
Angiogenesis is a multiscale process by which a primary blood vessel issues secondary vessel sprouts that reach regions lacking oxygen. Angiogenesis can be a natural process of organ growth and development or a pathological induced by a cancerous tumor.
arxiv  

Well posedness of an angiogenesis related integrodifferential diffusion model [PDF]

open access: yesApplied Mathematical Modelling 40 (2016) 5560-5575, 2016
We prove existence and uniqueness of nonnegative solutions for a nonlocal in time integrodifferential diffusion system related to angiogenesis descriptions. Fundamental solutions of appropriately chosen parabolic operators with bounded coefficients allow us to generate sequences of approximate solutions.
arxiv   +1 more source

Medium dependence of asphaltene agglomeration inhibitor efficiency [PDF]

open access: yesEnergy & Fuels vol.22, 2008, pp 1917 - 1922;, 2007
Applying chemical additives (molecule inhibitors or dispersants) is one of the common ways to control asphaltene agglomeration and precipitation. However, it is not clear why at some conditions the synthetic flocculation inhibitors as well as resins not only do not inhibit the asphaltene agglomeration,, they may also promote it, and why the increasing ...
arxiv   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Mesoscopic and continuum modelling of angiogenesis [PDF]

open access: yesJournal of Mathematical Biology February 2015, Volume 70, Issue 3, pp 485-532, 2014
Angiogenesis is the formation of new blood vessels from pre-existing ones in response to chemical signals secreted by, for example, a wound or a tumour. In this paper, we propose a mesoscopic lattice-based model of angiogenesis, in which processes that include proliferation and cell movement are considered as stochastic events.
arxiv   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Bioinformatics analysis reveals the potential target of rosiglitazone as an antiangiogenic agent for breast cancer therapy

open access: yesBMC Genomic Data, 2022
Highlights Recent studies have focused on the development of indirect angiogenesis inhibitors. Bioinformatics-based identification of potential rosiglitazone target genes to inhibit breast cancer angiogenesis.
Adam Hermawan, Herwandhani Putri
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

The Hemostatic System and Angiogenesis in Malignancy

open access: yesNeoplasia: An International Journal for Oncology Research, 2001
Coagulopathy and angiogenesis are among the most consistent host responses associated with cancer. These two respective processes, hitherto viewed as distinct, may in fact be functionally inseparable as blood coagulation and fibrinolysis, in their own ...
Marek Z. Wojtukiewicz   +3 more
doaj   +1 more source

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