Results 11 to 20 of about 19,335,204 (179)

Plasma angiopoietin-like protein 4 as a novel biomarker predicting 10-year mortality in a community-based population: a longitudinal cohort study

Archives of Medical Science
Introduction Angiopoietin-like protein 4 (ANGPTL4) is a hepatokine implicated in fat metabolism regulation. Its genetic inactivation has been associated with improved glucose homeostasis, while elevated plasma ANGPTL4 levels are observed in diabetic and ...
Kang-Chih Fan, Szu-Chi Chen, I-Weng Yen, Chia-Hung Lin, Chun-Heng Kuo, Ya-Pin Lyu, Hsien-Chia Juan, Mao-Shin Lin, Shu-Huei Wang, Hung-Yuan Li   +9 more
doaj   +2 more sources

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity

Journal of Lipid Research, 2019
Angiopoietin-like (ANGPTL) 8 is a secreted inhibitor of LPL, a key enzyme in plasma triglyceride metabolism. It was previously reported that ANGPTL8 requires another member of the ANGPTL family, ANGPTL3, to act on LPL.
Oleg Kovrov, Kristian Kølby Kristensen, Erika Larsson, Michael Ploug, Gunilla Olivecrona   +4 more
doaj   +1 more source

Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]

, 2013
We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Di Qin (107446), Seungmin Lee (68256), Qin, Di, Christian Kupatt (402864), Rabea Hinkel, Trenkwalder, Teresa, Rabea Hinkel (402865), Deindl, Elisabeth, Chillo, Omary, Teresa Trenkwalder (402861), Seungmin Lee, Christian Kupatt, Omary Chillo, Lee, Seungmin, Omary Chillo (402862), Kupatt, Christian, Elisabeth Deindl (402863), Di Qin, Hinkel, Rabea, Teresa Trenkwalder, Elisabeth Deindl   +20 more
core   +2 more sources

Angiopoietin-Like Protein 4 May Be an Interplay Between Serum Uric Acid and Triglyceride-Rich Lipoprotein Cholesterol

Frontiers in Cardiovascular Medicine, 2022
BackgroundAlthough the available evidence has indicated a link between elevated serum uric acid (SUA) level and dyslipidemia, the potential contribution of SUA on lipid profiles remains unclear.
Yani Peng, Die Hu, Die Hu, Qingting Luo, Daoquan Peng, Daoquan Peng   +5 more
doaj   +1 more source

Angiopoietin-like 4 (Angptl4) [PDF]

, 2012
Angiopoietin-like 4 (Angptl4) is a secreted protein modulating triacylglycerol homeostasis. Its transcription is induced by glucocorticoids, which act to elevate circulating Angptl4 levels during fasting.
Koliwad, Suneil K, Wang, Jen-Chywan, Gray, Nora E   +2 more
core   +1 more source

Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]

, 2009
Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad, Kain, Kevin C, Kevin C Kain, Kain Kevin C, Liles, W C, Conroy, Andrea L, Conroy Andrea L, Krudsood Srivicha, Erin I Lafferty, Srivicha Krudsood, Lafferty Erin I, Lovegrove, Fiona E, Lafferty, Erin I, Tangpukdee, Noppadon, Fiona E Lovegrove, W Conrad Liles, Tangpukdee Noppadon, Lovegrove Fiona E, Krudsood, Srivicha, Liles, W Conrad, Andrea L Conroy, Noppadon Tangpukdee   +21 more
core   +1 more source

The angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis is disrupted in patients with rheumatoid arthritis

Arthritis Research & Therapy, 2022
Background Modulators of triglyceride metabolism include lipoprotein lipase (LPL), angiopoietin-like protein 4 (ANGPTL4), and apolipoprotein C-3 (ApoC3).
Laura de Armas-Rillo, Juan Carlos Quevedo-Abeledo, Vanesa Hernández-Hernández, Antonia de Vera-González, Alejandra González-Delgado, José A. García-Dopico, Miguel Á. González-Gay, Iván Ferraz-Amaro   +7 more
doaj   +1 more source

A Review of free fatty acid-induced cell signaling, angiopoietin-like protein 4, and skeletal muscle differentiation

Frontiers in Physiology, 2022
Postnatal skeletal muscle differentiation from quiescent satellite cells is a highly regulated process, although our understanding of the contribution of nutritional factors in myogenesis is limited. Free fatty acids (FFAs) are known to cause detrimental
Yura Son, Chad M. Paton, Chad M. Paton
doaj   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A.   +24 more
core   +1 more source