Results 21 to 30 of about 75,735 (193)

Angiopoietin-like protein 4 and cardiovascular function in COPD [PDF]

BMJ Open Respir Res, 2017
Art. e000161, 8 S.INTRODUCTION: The coexistence of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) is frequent and might be inter-related through inflammation-related processes reflected by specific markers. Here, we studied
Welte, T., Holz, Olaf, Waschki, Benjamin, Rabe, K.F., Lichtinghagen, R., Watz, H., Magnussen, Helgo, Janciauskiene, S., Kirsten, Anne-Marie, Meyer, T.   +9 more
core   +2 more sources

Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through angiopoietin-like protein 4 [PDF]

Genes and Diseases, 2022
Podocyte injury is an important cause of proteinuria. Angiopoietin-like protein 4 (Angptl4) is a secreted glycoprotein and has a role in proteinuria. However, the exact role of Angptl4 in podocyte injury and its upstream regulators has not been clarified.
Xiujin Shen, Chunhua Weng, Yucheng Wang, Cuili Wang, Shi Feng, Xiayu Li, Heng Li, Hong Jiang, Haibing Wang, Jianghua Chen   +9 more
doaj   +2 more sources

Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP [PDF]

Molecular Metabolism, 2017
Objective: Angiopoietin-like protein-4 (ANGPTL4) is a circulating protein that is highly expressed in liver and implicated in regulation of plasma triglyceride levels.
Bodil Ingerslev, Jakob S. Hansen, Christoph Hoffmann, Jens O. Clemmesen, Niels H. Secher, Mika Scheler, Martin Hrabĕ de Angelis, Hans U. Häring, Bente K. Pedersen, Cora Weigert, Peter Plomgaard   +10 more
doaj   +2 more sources

A randomised, controlled, crossover study of the effect of diet on angiopoietin-like protein 4 (ANGPTL4) through modification of the gut microbiome [PDF]

Journal of Nutritional Science, 2016
Angiopoietin-like protein 4 (ANGPTL4) is a lipoprotein lipase inhibitor that is involved in lipid metabolism and angiogenesis. Animal studies have suggested that the ANGPTL4 protein is modulated by the gut microbiota, possibly through increased ...
Trine Blædel, Jacob B. Holm, Ulrik K. Sundekilde, Mette S. Schmedes, Anne L. Hess, Janne K. Lorenzen, Karsten Kristiansen, Trine K. Dalsgaard, Arne Astrup, Lesli H. Larsen   +9 more
doaj   +2 more sources

Angiopoietin‐Like Protein 4 Is a High‐Density Lipoprotein (HDL) Component for HDL Metabolism and Function in Nondiabetic Participants and Type‐2 Diabetic Patients [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundANGPTL4 (angiopoietin‐like protein 4) is a LPL (lipoprotein lipase) inhibitor and is present in high‐density lipoprotein (HDL). However, it is not defined whether ANGPTL4 in HDLs could affect HDL metabolism and function in type 2 diabetes ...
Long‐Yan Yang, Cai‐Guo Yu, Xu‐Hong Wang, Sha‐Sha Yuan, Li‐Jie Zhang, Jia‐Nan Lang, Dong Zhao, Ying‐Mei Feng   +7 more
doaj   +2 more sources

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Key Molecules of Triglycerides Pathway Metabolism Are Disturbed in Patients With Systemic Lupus Erythematosus

Frontiers in Immunology, 2022
BackgroundElevated triglycerides or triglyceride-rich lipoproteins are an additional cause of cardiovascular (CV) disease. Given that patients with systemic lupus erythematosus (SLE) have a high prevalence of premature CV disease and show an altered ...
Juan Carlos Quevedo-Abeledo, Candelaria Martín-González, Candelaria Martín-González, Carmen Ferrer-Moure, Laura de Armas-Rillo, Maria Vanesa Hernandez-Hernandez, Miguel Á. González-Gay, Miguel Á. González-Gay, Miguel Á. González-Gay, Iván Ferraz-Amaro, Iván Ferraz-Amaro   +10 more
doaj   +1 more source

Angiopoietin-like 4 (Angptl4) [PDF]

, 2012
Angiopoietin-like 4 (Angptl4) is a secreted protein modulating triacylglycerol homeostasis. Its transcription is induced by glucocorticoids, which act to elevate circulating Angptl4 levels during fasting.
Koliwad, Suneil K, Wang, Jen-Chywan, Gray, Nora E   +2 more
core   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A.   +24 more
core   +1 more source

Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis [PDF]

, 2003
We have investigated the function of mitotic kinesin-like protein (MKlp) 2, a kinesin localized to the central spindle, and demonstrate that its depletion results in a failure of cleavage furrow ingression and cytokinesis, and disrupts localization of ...
Mayer, Thomas U., Erich A. Nigg, Francis A. Barr, Neef, Rüdiger, Josephine Sutcliffe, Kopajtich, R., Rüdiger Neef, Nigg, E. A., Robert Kopajtich, Mayer, T. U., Thomas U. Mayer, Christian Preisinger, Preisinger, C., Neef, R., Sutcliffe, J., Barr, F. A., Nigg, Erich A., Sutcliffe, Josephine, Kopajtich, Robert, Preisinger, Christian, Barr, Francis A.   +20 more
core   +1 more source