Results 91 to 100 of about 107,707,414 (242)

Angiopoietin-1/Angiopoietin-2 Ratio for Prediction of Preeclampsia [PDF]

American Journal of Hypertension, 2009
A number of different biophysical and biochemical markers have been proposed as predictors of preeclampsia. Factors involved in the angiogenic balance are suggested as candidate markers. The purpose of this prospective, longitudinal cohort study was to determine whether a ratio between Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) can be used to ...
Marie, Bolin, Eva, Wiberg-Itzel, Anna-Karin, Wikström, Margareta, Goop, Anders, Larsson, Matts, Olovsson, Helena, Akerud   +6 more
openaire   +2 more sources

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

, 2002
VEGF and Angiopoietin-1 requisitely collaborate during blood vessel development. While Angiopoietin-1 obligately activates its Tie2 receptor, Angiopoietin-2 can activate Tie2 on some cells, while it blocks Tie2 activation on others.
Witte, MH, Witte, C, Campochiaro, PA, Renard, R, Martin, C, Gale, NW, McClain, J, Hackett, SF, Suri, C, Wiegand, SJ, Thurston, G, Yancopoulos, GD, Jackson, D, Wang, Q, Jackson, David   +14 more
core   +1 more source

Protective Role of Angiopoietin-1 in Experimental Pulmonary Hypertension [PDF]

Circulation Research, 2003
Angiopoietin-1 (Ang-1), a newly discovered ligand of the endothelial-specific tyrosine kinase receptor Tie-2, has been found to promote cell survival, vascular maturation, and stabilization. We hypothesized that Ang-1 gene transfer to the pulmonary microcirculation would improve pulmonary hemodynamics and vascular remodeling in ...
Yidan D, Zhao, Andrew I M, Campbell, Malcolm, Robb, Douglas, Ng, Duncan J, Stewart   +4 more
openaire   +2 more sources

Role of Angiopoietins in Development of Cancer and Neoplasia Associated with Viral Infection

Cells, 2020
Angiopoietin/tyrosine protein kinase receptor Tie-2 signaling in endothelial cells plays an essential role in angiogenesis and wound healing. Angiopoietin-1 (Ang-1) is crucial for blood vessel maturation while angiopoietin-2 (Ang-2), in collaboration ...
Xiaolan Yu, Fengchun Ye
doaj   +1 more source

Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage [PDF]

International Neurourology Journal, 2016
Purpose Microvascular endothelial integrity is important for maintaining the blood-brain barrier (BBB). However, subarachnoid hemorrhage (SAH) disrupts this integrity, making the BBB dysfunctional—an important pathophysiological change after SAH ...
Hua Gu, Zhen-Hai Fei, Yi-Qi Wang, Jian-Guo Yang, Chao-Hui Zhao, Yong Cai, Xing-Ming Zhong   +6 more
doaj   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Serum angiopoietin-1 as a prognostic marker in resected early stage lung cancer.

, 2009
PURPOSE: We evaluated the clinical significance of angiopoietins and vascular endothelial growth factor (VEGF) in patients with resected early stage lung cancer.
Lee, KB, Park, KJ, Park, JH, Kim, YS, Choi, JH, Chung, WY, Lee, HL, Choi, H, Hwang, SC, Sheen, SS, Kim, YB, Lee, S, Lee, KS   +12 more
core   +1 more source

Angiopoietin-1 enhances skeletal muscle regeneration in mice

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2015
Activation of muscle progenitor cell myogenesis and endothelial cell angiogenesis is critical for the recovery of skeletal muscle from injury. Angiopoietin-1 (Ang-1), a ligand of Tie-2 receptors, enhances angiogenesis and skeletal muscle satellite cell survival; however, its role in skeletal muscle regeneration after injury is unknown. We assessed the
Mahroo, Mofarrahi, Joseph M, McClung, Christopher D, Kontos, Elaine C, Davis, Bassman, Tappuni, Nicolay, Moroz, Amy E, Pickett, Laurent, Huck, Sharon, Harel, Gawiyou, Danialou, Sabah N A, Hussain   +10 more
openaire   +3 more sources

Association between periodontitis and exudative retinal detachment: A population‐based cohort study

Journal of Periodontology, EarlyView.
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu, Ming‐Ling Tsai, Tsu‐Hsuan Weng, Chi‐Hsiang Chung, Min‐Wen Fu, Wu‐Chien Chien   +5 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source