Results 101 to 110 of about 97,423,779 (276)

Transforming growth factor beta–related proteins promote axonal regeneration of injured dorsal root ganglion neurons

Neural Regeneration Research
Dorsal root ganglia neurons gradually lose their axonal regeneration ability during development and aging. To explore molecules that enhance axonal regeneration, we screened growth factors with differential gene expression patterns in the dorsal root ...
Yinying Shen, Peng Yang, Wenyu Dai, Xiaosong Gu, Sheng Yi   +4 more
doaj   +1 more source

Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria

, 2012
Objective: To investigate the relationship among the angiopoietin–Tie-2 system, retinopathy, and mortality in children with cerebral malaria. Design: A case–control study of retinopathy-positive vs.
Hawkes, Michael, Molyneux, Malcolm E, Seydel, Karl B., Conroy, Andrea L., Glover, Simon J., Taylor, Terrie E., Kain, Kevin C., Erdman, Laura K.   +7 more
core   +1 more source

High angiopoietin-2 levels associate with arterial inflammation and long-term glucocorticoid requirement in polymyalgia rheumatica [PDF]

, 2019
OBJECTIVES: PMR frequently co-occurs with GCA. So far, a simple biomarker for detecting concomitant arterial inflammation in PMR patients is lacking. Furthermore, biomarkers predicting disease course in PMR are awaited.
Boots, Annemieke, Bijzet, Johan; id_orcid, Maria Sandovici, van Sleen, Yannick, Abdulahad, Wayel; id_orcid, Yannick van Sleen, Boots, Annemieke M. H., Brouwer, Elisabeth, Annemieke Boots, Wayel Abdulahad, van der Geest, Kornelis; id_orcid, Elisabeth Brouwer, Sandovici, Maria; id_orcid, van der Geest, Kornelis S. M.; id_orcid, Kornelis van der Geest, Abdulahad, Wayel H.; id_orcid, Johan Bijzet   +16 more
core   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer.

PLoS ONE, 2020
BackgroundAntiangiogenic therapy, although part of standard treatment in ovarian cancer, has variable efficacy. Furthermore, little is known about the prognostic biomarkers and factors influencing angiogenesis in cancer tissue.
Minna Sopo, Hanna Sallinen, Kirsi Hämäläinen, Annukka Kivelä, Seppo Ylä-Herttuala, Veli-Matti Kosma, Leea Keski-Nisula, Maarit Anttila   +7 more
doaj   +1 more source

Expression and significance of angiopoietin-2 in gastric cancer

World Journal of Gastroenterology, 2004
To investigate the expression and pathological factors of Angiopoietin-2 (Ang-2) in primary gastric cancers and adjacent normal tissues.The expression of Angiopoietin-2 and VEGF were studied in 72 primary gastric cancers and adjacent normal tissues from the same patients by semi-quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) and ...
Xiao-Dong, Sun, Xing-E, Liu, Jin-Min, Wu, Xiu-Jun, Cai, Yi-Ping, Mou, Jun-Da, Li   +5 more
openaire   +2 more sources

Real‐world incidence and clinical characteristics of intraocular inflammation following intravitreal faricimab therapy: A safety study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider, Leyla Turan, Farah Arif, Jakob Bjerager, Oliver Niels Klefter, Carsten Faber, Yousif Subhi, Javad Nouri Hajari   +7 more
wiley   +1 more source

Intravitreal faricimab in patients with nAMD: French data from the Fight Retinal Blindness! Registry

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess real‐world outcomes of intravitreal faricimab in French patients with neovascular age‐related macular degeneration (nAMD) previously treated with vascular endothelial growth factor (VEGF) inhibitors using data from the Fight Retinal Blindness! (FRB!) Registry.
Eloi Debourdeau, Déborah Harboun, Pierre‐Henry Gabrielle, Yohei Hashimoto, Chloe Chamard, Frederic Michon, Benjamin Wolff, Héloïse Torres‐Villaros, Audrey Giocanti‐Auregan, Mark Gillies, Catherine Creuzot–Garcher, Vincent Daien   +11 more
wiley   +1 more source

Angiopoietin 1 influences ischemic reperfusion renal injury via modulating endothelium survival and regeneration

Molecular Medicine, 2019
Background Damage to the endothelium due to ischemia reperfusion injury (IRI) leads to a disruption of the microvasculature, which could be influenced by angiopoietin 1 via its effects on endothelium.
Wen-Chih Chiang, Yu-Chin Huang, Ten-I Fu, Ping-Min Chen, Fan-Chi Chang, Chun-Fu Lai, Vin-Cent Wu, Shuei-Liong Lin, Yung-Ming Chen   +8 more
doaj   +1 more source

The role of angiopoietin-2 in progressive renal fibrosis

Journal of the Formosan Medical Association, 2013
With increasing prevalence worldwide, chronic kidney disease (CKD) has drawn great attention. In the case of progressive renal disease, decline in renal function correlates with the extent of interstitial fibrosis, irrespective of the initiating pathology.
Fan-Chi Chang, Shuei-Liong Lin
openaire   +3 more sources