Results 151 to 160 of about 97,423,779 (276)
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
Advanced Functional Materials, Volume 36, Issue 86, 26 October 2026.A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics
Advanced Therapeutics, Volume 9, Issue 10, October 2026.Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker +4 more
wiley +1 more source
Advanced Science, Volume 13, Issue 58, 19 October 2026.In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu +7 more
wiley +1 more source
Evaluation of tissue and serum levels of VEGF, angiopoietin-1 and angiopoietin-2 in lung cancer
, 2011 Akciğer kanseri dünyadaki kansere bağlı ölümlerin en sık nedeni olup, yılda bir milyondan fazla kişi de ölüme yol açmaktadır. Solit tümörler 2-3 mm3 boyuttan sonra gerekli oksijen ve besin ihtiyacını diffüzyon ile karşılayamaz ve anjiogeneze ihtiyaç ...
YUSUFOĞLU, NURHİLAL
core
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, Volume 13, Issue 59, 23 October 2026.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Advanced Science, Volume 13, Issue 58, 19 October 2026.Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
Correction: Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia. [PDF]
PLoS ONE, 2015 PLOS ONE Staff
doaj +1 more source
Advanced Science, Volume 13, Issue 58, 19 October 2026.This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACT Breast cancer remains a leading cause of cancer‐related mortality among women worldwide, with treatment resistance, disease heterogeneity, and therapy‐associated toxicities limiting clinical outcomes. Its major clinically relevant subtypes, including oestrogen receptor‐positive (ER+), human epidermal growth factor receptor 2‐positive (HER2 ...
Nireshini Reddy +5 more
wiley +1 more source
Angiopoietin-2 and Progressive Kidney Disease. [PDF]
J Am Soc NephrolJeansson M.
europepmc +1 more source