Results 171 to 180 of about 97,423,779 (276)
ABSTRACT Aims Atezolizumab combined with bevacizumab (AB therapy) is a standard first‐line treatment for advanced hepatocellular carcinoma (HCC). However, clinically useful biomarkers for predicting therapeutic efficacy and severe adverse events (AEs) remain limited.
Naoki Nishimura +12 more
wiley +1 more source
Corrigendum to Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction. [PDF]
Lee SJ +10 more
europepmc +1 more source
Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi +9 more
wiley +1 more source
Engineering Novel Angiopoietin Receptor Ligands
Angiopoietin-1 is a multimeric glycoprotein which signals through the vascular endothelial Tie2 receptor to protect against inflammation and leakage, an effect antagonised by the selectively upregulated antagonist angiopoietin-2. In many pathologies this
Andrew James Moss (7659908)
core
Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
Serum Angiopoietin-1 and Angiopoietin-2 as Biomarkers of Pulmonary Hemodynamic Burden in COPD-Associated Pulmonary Hypertension: A Cross-Sectional Study. [PDF]
Bajpai J +7 more
europepmc +1 more source
ABSTRACT The aim of this study was to characterize the proteome of sperm and seminal plasma (SP) from rams with high semen freezability (HF) and low semen freezability (LF). Eleven ejaculates were collected from 12 rams, at 3‐day intervals, and cryopreserved (132 semen samples).
Wallisson Bruno de Morais Pacheco +14 more
wiley +1 more source
Urinary angiopoietin-2 as a biomarker of kidney outcomes in critical illness: same label, different signals. [PDF]
Zhang R.
europepmc +1 more source
Small Leucine‐Rich Proteoglycans in Cancer: Three Decades of Discovery
ABSTRACT Small leucine‐rich proteoglycans (SLRPs) are a well‐known family of extracellular matrix (ECM) molecules. They consist of five classes with 18 different protein cores originally recognized as having a physically supportive component to the extracellular structure and tissue integrity.
Gabriel J. Pascal +5 more
wiley +1 more source

