Results 111 to 120 of about 96,838 (221)
Glucocorticoid Receptor and Adipocyte Biology. [PDF]
, 2018 Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A +2 more
core +2 more sources
The piranha genome provides molecular insight associated to its unique feeding behavior [PDF]
, 2019 The piranha enjoys notoriety due to its infamous predatory behavior but much is still not understood about its evolutionary origins and the underlying molecular mechanisms for its unusual feeding biology.
Adolfi, Mateus +9 more
core +2 more sources
iMeta, EarlyView.We utilized single‐cell RNA sequencing (scRNA‐seq) to investigate cellular heterogeneity and signaling networks in aortic dissection (AD) tissues compared to adjacent normal tissues. The analysis identified five smooth muscle cell (SMC) subtypes, with SMC2 linked to fibrosis and SMC3 associated with inflammation.
Liang Shao +12 more
wiley +1 more source
, 2017 Aptamers are single stranded DNA, RNA or peptide sequences having the ability to bind a variety of specific targets (proteins, molecules as well as ions).
Alfinito, E., Cataldo, R., Reggiani, L.
core +1 more source
Kaposiform hemangioendothelioma: Diagnosis and treatment
Pediatric Investigation, EarlyView.Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian +5 more
wiley +1 more source
Pioglitazone administration alters ovarian gene expression in aging obese lethal yellow mice
Reproductive Biology and Endocrinology, 2008 Background Women with polycystic ovary syndrome (PCOS) are often treated with insulin-sensitizing agents, e.g. thiazolidinediones (TZD), which have been shown to reduce androgen levels and improved ovulatory function.
Weber Mitch +3 more
doaj +1 more source
mRNA Expression of Ovine Angiopoietin-like Protein 4 Gene in Adipose Tissues [PDF]
Asian-Australasian Journal of Animal Sciences, 2016 Angiopoietin-like protein 4 (ANGPTL4) is involved in a variety of functions, including lipoprotein metabolism and angiogenesis. To reveal the role of ANGPTL4 in fat metabolism of sheep, ovine ANGPTL4 mRNA expression was analyzed in seven adipose tissues ...
Jing Zhang +6 more
doaj +1 more source
Small Methods, EarlyView.This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source
Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin. [PDF]
, 2014 Angiopoietin-like 4 (Angptl4) is a glucocorticoid receptor (GR) primary target gene in hepatocytes and adipocytes. It encodes a secreted protein that inhibits extracellular LPL and promotes adipocyte lipolysis.
Chen, Tzu-Chieh +6 more
core +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen +5 more
wiley +1 more source