ABSTRACT Peripheral artery disease (PAD) is a progressive atherothrombotic disorder affecting more than 230 million people worldwide. Conventional animal models of chronic hindlimb ischemia (HLI) are highly invasive, technically challenging, fail to account for anatomical variation, and may not accurately recapitulate progressive PAD pathophysiology ...
Oliver Kitzerow +4 more
wiley +1 more source
ABSTRACT Background Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently with cognition in BD ...
Alexandra J. M. Beunders +21 more
wiley +1 more source
RAS Inhibitor RMC‐7977 Blocks Vascular Overgrowth of NRASQ61R Mutant Endothelial Cells
ABSTRACT RAS mutations occur in patients with several types of vascular anomalies, but effective treatments remain limited. To address this need, we evaluated the RAS (ON) multi‐selective inhibitor RMC‐7977 in human endothelial cells (ECs) expressing the NRASQ61R mutation found in kaposiform lymphangiomatosis (KLA).
Sara Alharbi +6 more
wiley +1 more source
Aim: The aim of this study was to investigate the effect of ANGPTL 2and ANGPTL 8 on the diagnosis of PCOS.Material and Method: Eighty patients were included in the study. Inthis study, control group (n= 40) and polycystic ovary syndrome group (n=40)were formed demographic data and clinical characteristics of the patients havebeen registered as a ...
openaire +1 more source
Angiopoietin-like Proteins 4 and 8 in Diabetic Complications: Associations with Neuropathy and Metabolic Parameters in Type 2 Diabetes. [PDF]
Naydenov Y +6 more
europepmc +1 more source
Pemafibrate Increases Circulating Angiopoietin-like Proteins 3 and 4 Without Promoting Pro-Atherogenic Changes in LDL and HDL Subspecies: A Post-Hoc Analysis of the PRESTIGE Study. [PDF]
Hirano T +8 more
europepmc +1 more source
Angiopoietin-like Proteins and Lipoprotein Lipase: The Waltz Partners That Govern Triglyceride-Rich Lipoprotein Metabolism? Impact on Atherogenesis, Dietary Interventions, and Emerging Therapies. [PDF]
Gugliucci A.
europepmc +1 more source
Correlation between angiopoietin-like proteins in inflammatory mediators in peripheral blood and severity of coronary arterial lesion in patients with acute myocardial infarction. [PDF]
Cao Y +5 more
europepmc +1 more source
Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits. [PDF]
Mehta N +6 more
europepmc +1 more source

