Results 151 to 160 of about 22,958 (190)

Endothelial Glycocalyx in Kidney Transplantation: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Navratil P, Tranova MN, Haluska A, Lesko M, Gunka I, Astapenko D.   +5 more
europepmc   +1 more source

Aqueous Humor Biomarkers, Efficacy, and Safety in Patients with Naïve Diabetic Macular Edema Treated with Faricimab: The ALTIMETER Study. [PDF]

Ophthalmol Sci
Schlottmann PG, Fawzi AA, Amador M, Dieckmann A, Gibson K, Glittenberg C, Jhaveri C, Kotak A, Mar F, Neubert A, Sheth VS, Souverain A, Titz B, Vazquez-Lombardi C, Wykoff CC, Ziemssen F, Vujosevic S.   +16 more
europepmc   +1 more source

Angiopoietin-Like Protein 3 Inhibition: A Key to Silencing Residual Lipid Risk?

Journal of the American College of Cardiology
Stroes, Erik S. G., Weijs, Bram M., Annink, Maxim E.   +2 more
openaire   +2 more sources

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Angiopoietin-like proteins in atherosclerosis

Clinica Chimica Acta, 2021
Atherosclerosis, as a chronic inflammatory disease within the arterial wall, is a leading cause of morbidity and mortality worldwide due to its role in myocardial infarction, stroke and peripheral artery disease. Additional evidence is emerging that the angiopoietin-like (ANGPTL) family of proteins participate in the pathology of this disease process ...
Chi Zhang
exaly   +3 more sources

Angiopoietins and Angiopoietin-Like Proteins in Angiogenesis

Endothelium: Journal of Endothelial Cell Research, 2006
Vascular network formation requires several endothelial cell growth factors. These factors have a potent angiogenic effect, and their precise coordination is essential for vascular development. Among them, angiopoietins function through the Tie2 receptor, whose signaling is critical to regulate vascular stabilization and remodeling.
Yoshiaki Kubota, Toshio Suda, Yuichi Oike   +2 more
exaly   +3 more sources

Angiopoietin-like proteins in multiple sclerosis

Journal of Neuroimmunology, 2019
Angiopoietin-like proteins (ANGPTLs) are a group of proteins with functions in lipid metabolism, angiogenesis, and inflammation. Here, we investigated their involvement in multiple sclerosis (MS) progression and response to treatment in 100 MS patients and 77 healthy controls. ANGPTLs significantly associated with MS progression and response to therapy.
Raed Alroughani, Mohamed Abu-Farha, Rabeah Altemaimi   +2 more
exaly   +3 more sources

Regulation of triglyceride metabolism by Angiopoietin-like proteins

Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2012
Plasma triglyceride concentrations are determined by the balance between production of the triglyceride-rich lipoproteins VLDL and chylomicrons in liver and intestine, and their lipoprotein lipase-mediated clearance in peripheral tissues. In the last decade, the group of Angiopoietin-like proteins has emerged as important regulators of circulating ...
Sander Kersten, Frits Mattijssen
exaly   +4 more sources

The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism

Trends in Cardiovascular Medicine, 2008
Recently, a family of proteins structurally similar to the angiogenic regulating factors angiopoietins was identified and designated "angiopoietin-like proteins" (Angptls). Encoded by seven genes, Angptls 1 to 7 all possess an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain, both characteristic of angiopoietins.
Tai Hato, Yuichi Oike, Mitsuhisa Tabata   +2 more
exaly   +3 more sources

Angiopoietin-Related/Angiopoietin-Like Proteins Regulate Angiogenesis

International Journal of Hematology, 2004
A general understanding of the molecular mechanisms underlying angiogenesis is emerging from the analysis of targeted mutations in vasculature-related genes. These analyses reveal that angiopoietin signaling through the TIE2 receptor is involved in regulating angiogenesis.
Toshio Suda, Suda Toshio, Oike Yuichi
exaly   +3 more sources