Results 101 to 110 of about 35,409 (231)
Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8595-8601, September 2026.ABSTRACT Objective The importance of randomised trials for discerning an intervention's effect rests on randomisation's ability to create groups with (on average) equal hazards of future outcomes. The frequency with which this does not occur in well‐designed large trials with a high event rate was studied.
Hertzel C. Gerstein +5 more
wiley +1 more source
Journal of Internal Medicine, Volume 300, Issue 3, Page 312-328, September 2026.Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca +16 more
wiley +1 more source
Medical and Veterinary Entomology, Volume 40, Issue 3, Page 659-671, September 2026.Lucilia sericata larvae secrete bioactive compounds that promote wound debridement and antimicrobial defence in chronic tissue injuries. Achillea sintenisii extract offers phytotherapeutic support, enhancing healing through anti‐inflammatory and regenerative properties. Diabetic Wistar rats were treated topically with Furacin®, larval secretions, plant
Nevra Polat +2 more
wiley +1 more source
Терапевтический архив, 2015 Aim. To study the urinary excretion of the molecular factors regulating angiogenesis, such as vascular endothelial growth factor type A (VEGF-A), thrombospondin 1 (THBS1), and angiopoietin 2 (ANGPT2), versus that of the urinary markers of renal injury ...
M Yu Shvetsov +5 more
doaj
Advanced Science, Volume 13, Issue 43, 3 August 2026.A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che +9 more
wiley +1 more source
Advanced Science, Volume 13, Issue 45, 13 August 2026.Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li +8 more
wiley +1 more source
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Comprehensive Physiology, Volume 16, Issue 4, August 2026.Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.Mesenchymal stem cell‐derived exosomes (MSC‐sEVs) show preclinical promise for cardiac repair via anti‐inflammatory, anti‐apoptotic, pro‐angiogenic and anti‐fibrotic effects. However, translational hurdles remain, including non‐standardized isolation, unvalidated potency assays, incomplete GMP manufacturing, and lack of completed Phase II/III trials ...
Sakhavat Abolhasani +2 more
wiley +1 more source
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
eFood, Volume 7, Issue 4, August 2026.Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source
Lycopene Increases Skeletal Muscle Mass by Promoting Myoblast Differentiation
Food Science &Nutrition, Volume 14, Issue 8, August 2026.Lycopene supplementation could increase skeletal muscle mass by promoting myoblast differentiation and muscle protein synthesis. Mechanistic analysis revealed that lycopene could activate ERα, and ERα activation facilitated myogenic differentiation and myotube formation. ABSTRACT Muscle differentiation is a necessary process for the growth, development
Wanxue Wen +6 more
wiley +1 more source