Renin Angiotensin System (RAS) Pathways in COVID Pathogenesis
Background – Covid-19 pandemic has posed some rare diagnostic & therapeutic challenges. Recurrent waves of varying severity are caused by ongoing mutations in the virus. It is vital to understand the fundamentals of Renin Angiotensin System (RAS) pathway
Sampreeti Mukherjee, Minu Bajpai
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Effects of Vasodepressor vs. Vasopressor Arms of Renin Angiotensin System on Renal Hemodynamic Regulation in Renal Ischemia-Reperfusion Injury; Sex Difference [PDF]
The exact mechanisms involved in acute renal injury (AKI) due to renal ischemia-reperfusion (IR) are not fully understood, although it has been shown that the renin-angiotensin system (RAS) may play an important role in IR-associated AKI.
Farzaneh Karimi +4 more
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Endogenous peptides are important mediators in cell communication, being consequently involved in many physiological processes. Their use as therapeutic agents is limited due to their poor pharmacokinetic profile. To circumvent this drawback, alternative
Juan J. Perez
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Anti‐inflammatory and immune‐modulatory therapies have been proposed for the treatment of COVID‐19 and its most serious complications. Among others, the use of mesenchymal stromal cells (MSCs) is under investigation given their well‐documented anti ...
Maria A. Avanzini +13 more
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Angiotensin peptides in the regulation of adrenal cortical function
The adrenal cortex plays a key role in the regulation of metabolism, salt and water homeostasis and sex differentiation by synthesizing glucocorticoid, mineralocorticoid and androgen hormones.
Gian Paolo Rossi +4 more
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Pathological Role of Angiotensin II in Severe COVID-19
The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
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The Higher Response of Vascular Endothelial Growth Factor and Angiotensin-II to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome [PDF]
Background This research investigated the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-II (AT-II) to ovarian stimulation during 24 hours in patients with polycystic ovary syndrome (PCOS).
Junwei Qu +5 more
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NO, ROS, RAS, and PVAT: More Than a Soup of Letters
Perivascular adipose tissue (PVAT) has recently entered in the realm of cardiovascular diseases as a putative target for intervention. Notwithstanding its relevance, there is still a long way before the role of PVAT in physiology and pathology is fully ...
Clarissa Germano Barp +2 more
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Temporal profile and mechanisms of the prompt sympathoexcitation following coronary ligation in Wistar rats [PDF]
Our aim was to assess the timing and mechanisms of the sympathoexcitation that occurs immediately after coronary ligation. We recorded thoracic sympathetic (tSNA) and phrenic activities, heart rate (HR) and perfusion pressure in Wistar rats subjected to ...
Abdala, Ana Paula +5 more
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Duration of rheumatoid arthritis changes blood levels of angiotensin and aldosterone
The article presents data on the influence of rheumatoid arthritis (RA) duration on changes in blood levels of angiotensin (ATII) and aldosterone (ALD). Objective — To examine the changes in the activity of the renin-angiotensin-aldosterone system (RAAS)
Boris A. Rebrov +2 more
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