Results 1 to 10 of about 362,070 (215)
Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing's syndrome. [PDF]
Endocr ConnectBackground: Arterial hypertension and left ventricular hypertrophy and remodeling are independent cardiovascular risk factors in patients with Cushing’s syndrome. Changes in the renin–angiotensin system and in the mineralocorticoid axis activity could be
Wolf P +13 more
europepmc +2 more sources
NO, ROS, RAS, and PVAT: More Than a Soup of Letters
Frontiers in Physiology, 2021 Perivascular adipose tissue (PVAT) has recently entered in the realm of cardiovascular diseases as a putative target for intervention. Notwithstanding its relevance, there is still a long way before the role of PVAT in physiology and pathology is fully ...
Clarissa Germano Barp +2 more
doaj +1 more source
Angiotensin peptides in the regulation of adrenal cortical function
Exploration of Medicine, 2021 The adrenal cortex plays a key role in the regulation of metabolism, salt and water homeostasis and sex differentiation by synthesizing glucocorticoid, mineralocorticoid and androgen hormones.
Gian Paolo Rossi +4 more
doaj +1 more source
Stem Cells Translational Medicine, 2021 Anti‐inflammatory and immune‐modulatory therapies have been proposed for the treatment of COVID‐19 and its most serious complications. Among others, the use of mesenchymal stromal cells (MSCs) is under investigation given their well‐documented anti ...
Maria A. Avanzini +13 more
doaj +1 more source
Pathological Role of Angiotensin II in Severe COVID-19
TH Open, 2020 The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
doaj +1 more source
Biomedicines, 2021 Endogenous peptides are important mediators in cell communication, being consequently involved in many physiological processes. Their use as therapeutic agents is limited due to their poor pharmacokinetic profile. To circumvent this drawback, alternative
Juan J. Perez
doaj +1 more source
Pharmaceuticals, 2023 Aim: Angiotensin II (AngII) is known to play a significant part in the development of breast cancer by triggering cell propagation of breast cancer, tumor angiogenesis, and regulating tumor invasion and cell migration. AngII arbitrates its action via two
Subhani M. Okarvi
doaj +1 more source
The Higher Response of Vascular Endothelial Growth Factor and Angiotensin-II to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome [PDF]
International Journal of Fertility and Sterility, 2015 Background This research investigated the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-II (AT-II) to ovarian stimulation during 24 hours in patients with polycystic ovary syndrome (PCOS).
Junwei Qu +5 more
doaj +1 more source
Renin Angiotensin System (RAS) Pathways in COVID Pathogenesis
National Board of Examinations Journal of Medical Sciences, 2023 Background – Covid-19 pandemic has posed some rare diagnostic & therapeutic challenges. Recurrent waves of varying severity are caused by ongoing mutations in the virus. It is vital to understand the fundamentals of Renin Angiotensin System (RAS) pathway
Sampreeti Mukherjee, Minu Bajpai
doaj +1 more source
Angiotensin System Autoantibodies Correlate With Routine Prognostic Indicators for COVID-19 Severity
Frontiers in Medicine, 2022 ObjectiveWe previously showed that angiotensin type-1 receptor and ACE2 autoantibodies (AT1-AA, ACE2-AA) are associated with COVID-19 severity. Our aim is to find correlations of these autoantibodies with routine biochemical parameters that allow an ...
Carmen M. Labandeira +8 more
doaj +1 more source