Results 91 to 100 of about 34,610,957 (287)

A Review on Current Challenges and Knowledge Gaps in Artificial Stone Silicosis

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background The global emergence of artificial stone (AS) silicosis represents a critical occupational health challenge. The aim of this systematic review is to provide an overview of the clinical, functional, radiological, and occupational characteristics of patients affected by AS silicosis at the time of diagnosis, and to identify current ...
Paola Mason   +8 more
wiley   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun   +7 more
wiley   +1 more source

Peran Angiotensin 1-7 pada Penyakit Ginjal Kronik

open access: yesJurnal Ilmu Kesehatan Indonesia
Latar Belakang:  Penyakit ginjal kronik (PGK) ditandai penurunan progresif fungsi ginjal. Pada patogenesisnya, sistem renin–angiotensin–aldosteron (RAAS) berperan sentral.
Dinda Putri Sofiani, Harnavi Harun
doaj   +1 more source

Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation?

open access: yesHeart Failure Reviews, 2019
Atrial fibrillation (AF) is a significant cause of morbidity and mortality as well as a public health burden considering the high costs of AF-related hospitalizations. Pre-clinical and clinical evidence showed a potential role of the renin angiotensin system (RAS) in the etiopathogenesis of AF.
Mascolo, Annamaria   +8 more
openaire   +5 more sources

DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]

open access: yes, 2012
The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Eisenmenger, Wolfgang   +22 more
core   +1 more source

Angiotensin-(1–7) blocks the angiotensin II-stimulated superoxide production

open access: yesPharmacological Research, 2007
Angiotensin (Ang)-(1-7), a bioactive compound of the renin-angiotensin system, exerts effects leading to blood pressure reduction which counterbalance Ang II pressor actions. The present study was conducted to examine Ang-(1-7) and Ang II effects on superoxide anion production in rat aorta using the lucigenin chemiluminescence method.
Polizio, Ariel Héctor   +3 more
openaire   +3 more sources

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

open access: yesThe Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) [PDF]

open access: yesHypertension, 2006
This lecture summarizes the chronology and rationale that led to the discovery of angiotensin-(1-7) as a hormone that, in its own right, opposes the vasoconstrictor and proliferative actions of angiotensin II. The work discussed here additionally analyzes the newest findings on angiotensin-converting enzyme 2, the angiotensin-converting enzyme ...
openaire   +1 more source

Role of the vasodilator peptide angiotensin-(1–7) in cardiovascular drug therapy

open access: yes, 2007
Christoph Schindler1, Peter Bramlage1, Wilhelm Kirch1, Carlos M Ferrario21Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany; 2Hypertension and Vascular Disease Center, Wake Forest University, School of
Carlos M Ferrario   +3 more
core  

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo   +7 more
wiley   +1 more source

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