Results 101 to 110 of about 77,701 (209)

Angiotensin II Type 1 Receptor Blockers [PDF]

open access: yesValue in Health, 2018
L Luan, H Hu, SC Li
openaire   +1 more source

Pharmacological and clinical profile of telmisartan, a selective angiotensin II type-1 receptor blocker

open access: yesFolia Pharmacologica Japonica, 2004
Telmisartan (Micardis) is a potent, long-lasting, nonpeptide angiotensin II type-1 (AT(1)) receptor blocker (ARB) that is indicated for the treatment of essential hypertension. In receptor binding studies, telmisartan showed a high affinity and selectivity for the human AT(1) receptors compared with AT(2) receptors and a slower dissociation rate from ...
Motohiko, Chachin   +4 more
openaire   +3 more sources

Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

open access: yes, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz   +17 more
core   +3 more sources

Polymorphisms of the angiotensin II type 1 receptor gene affect antihypertensive response to angiotensin receptor blockers in hypertensive Chinese

open access: yesGenetics and Molecular Research, 2013
The renin-angiotensin-aldosterone system plays a key role in regulating blood pressure by maintaining vascular tone and the water/sodium balance. Many antihypertensive drugs target the renin-angiotensin-aldosterone system, but the effect differs considerably among hypertensive patients.
H T, Gong   +6 more
openaire   +2 more sources

Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]

open access: yes, 2015
Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh   +6 more
core   +2 more sources

Renovascular and renoprotective properties of telmisartan: clinical utility

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2010
Marco Ladino, Ivonne Hernandez SchulmanNephrology-Hypertension Section, Veterans Affairs Medical Center and Division of Nephrology and Hypertension and Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, FL ...
Marco Ladino, Ivonne Hernandez Schulman
doaj  

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

open access: yes, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFβ signaling

open access: yesFEBS Open Bio, 2014
Staphylococcal nuclease domain containing-1 (SND1) is overexpressed in human hepatocellular carcinoma (HCC) patients and promotes tumorigenesis by human HCC cells.
Prasanna K. Santhekadur   +9 more
doaj   +1 more source

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