Dementia Risk With Combined Statin and Antihypertensive Drugs That Increase Versus Decrease Angiotensin-II Formation: Findings From the 45 and Up Study. [PDF]
Int J Geriatr PsychiatryBelachew EA +3 more
europepmc +1 more source
Angiotensin II type-1 receptor blockers enhance the effects of bevacizumab-based chemotherapy in metastatic colorectal cancer patients. [PDF]
Mol Clin Oncol, 2015 Osumi H +5 more
europepmc +1 more source
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
Renin-Angiotensin Signaling and Vascular Function: Insights into Health and Disease. [PDF]
Acta Physiol (Oxf)Bertoldi G, Sonkusare SK.
europepmc +1 more source
Risk factors for infection after hysterectomy for benign disease
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Pre‐ and perioperative risk factors; including high BMI, immunomodulatory treatment, endometriosis, younger age, and previous abdominal or cesarean surgery can be integrated into clinical risk assessment to identify women at increased risk of postoperative infectious morbidity and to guide individualized preventive strategies after hysterectomy ...
Sophia Ehrström +2 more
wiley +1 more source
Hormonal Modulation in Chronic Coronary Syndrome: From Neurohormonal Activation to Endocrine Targets. [PDF]
BiomedicinesBrie AD, Popescu R, Mornoș C, Brie DM.
europepmc +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Commonly prescribed NSAIDs, PPIs and SSRIs were associated with a higher risk of microscopic colitis after propensity score matching, whereas ACE inhibitors, ARBs and statins showed no significant association. ABSTRACT Background The association between medications—including non‐steroidal anti‐inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs ...
Yassine Kilani +6 more
wiley +1 more source
Mapping Pharmacogenomic Determinants of Adverse Drug Reactions in Hypertension: A Systematic Review. [PDF]
Pharmaceuticals (Basel)Dsouza VS +6 more
europepmc +1 more source
The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source