Results 201 to 210 of about 39,438,208 (302)

A physiology-based mathematical model of the renin-angiotensin system, bone remodeling, and calcium homeostasis: Effects of estrogen and renin-angiotensin system inhibitors. [PDF]

PLoS Comput Biol
Stadt MM, Ralph VA, Layton AT.
europepmc   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

The Role of the Renin-Angiotensin-Aldosterone System in Hypertensive Emergencies. [PDF]

Biomedicines
Minari TP, Cosenso-Martin LN, Uyemura JRR, Santos AMP, Lopes VDS, Franco RF, Vieira-da-Silva MA, Oliveira KA, Almeida MA, Yugar-Toledo JC, Vilela-Martin JF.   +10 more
europepmc   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Impact of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on cardiovascular and non-cardiovascular outcomes in patients at high/very-high cardiovascular risk without heart failure: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials ^†. [PDF]

Eur Heart J Open
Masi S, Savarese G, Orsini N, Strauss MH.   +3 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Efficacy of finerenone in reducing proteinuria in diabetic kidney disease on dapagliflozin and telmisartan: A disease-modifying approach. [PDF]

World J Nephrol
Jose A, Kamrul-Hasan ABM, Fernandez CJ, Pappachan JM.   +3 more
europepmc   +1 more source

Effect of the angiotensin II type 1 receptor blocker candesartan on cardiovascular events

Journal of the American College of Cardiology, 2002
Kondo, Junichiro, Sone, Takahito, Tsubo, Hideyuki, Mukawa, Hiroaki, Morishima, Itsuro, Uesugi, Michitaka, Kosaka, Takashi, Yoshida, Tomohiro   +7 more
openaire   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Aldosterone Synthase Inhibition in Diabetes and Cardiorenal Metabolic Disease. [PDF]

J Diabetes
Bloomgarden Z.
europepmc   +1 more source