Results 271 to 280 of about 39,438,208 (302)
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The American Journal of Cardiology, 1999
The angiotensin II receptor blockers (ARBs) are safe and effective agents in the treatment of hypertension, and they have potential in treating other cardiovascular disorders such as heart failure. These drugs share a common mechanism of action: They selectively block the angiotensin type 1 (AT1) receptor.
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The angiotensin II receptor blockers (ARBs) are safe and effective agents in the treatment of hypertension, and they have potential in treating other cardiovascular disorders such as heart failure. These drugs share a common mechanism of action: They selectively block the angiotensin type 1 (AT1) receptor.
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Class- and Molecule-specific Differential Effects of Angiotensin II Type 1 Receptor Blockers
Current Pharmaceutical Design, 2013Angiotensin II (Ang II) type 1 (AT1) receptor is a member of the G protein-coupled receptor superfamily and contains 359 amino acids. AT1 receptor blockers (ARBs, e.g., eprosartan, losartan, candesartan, valsartan, telmisartan, olmesartan, irbesartan, and azilsartan) have been developed and are available for clinical use, and basic and clinical studies
Satoshi, Imaizumi +5 more
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Possible benefits of azilsartan compared with other angiotensin II type 1 receptor blockers
Hypertension Research, 2014Possible benefits of azilsartan compared with other angiotensin II type 1 receptor ...
Shin-Ichiro, Miura, Keijiro, Saku
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Journal of Hypertension, 1997
RENIN-ANGIOTENSIN SYSTEM AND HYPERTENSION: The renin-angiotensin system is integral to the mechanisms that sustain hypertension. Hypertensive patients with inappropriately high renin levels have an increased risk of cardiovascular events, and thus there is continuing interest in treating hypertension with drugs that not only reduce blood pressure but ...
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RENIN-ANGIOTENSIN SYSTEM AND HYPERTENSION: The renin-angiotensin system is integral to the mechanisms that sustain hypertension. Hypertensive patients with inappropriately high renin levels have an increased risk of cardiovascular events, and thus there is continuing interest in treating hypertension with drugs that not only reduce blood pressure but ...
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Angiotensin II type 1 receptor blocker inhibits pulmonary injury.
Clinical and investigative medicine. Medecine clinique et experimentale, 2005Pulmonary damage and fibrosis may be the result of diverse forms of injury and there is an association between pulmonary diseases and cardiovascular events. The purpose of this study was to evaluate the effects of an angiotensin II type 1 receptor blocker, valsartan, on systemic, cellular, and fibrotic consequences of pulmonary injury induced by the ...
G B John, Mancini, Nasreen, Khalil
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International journal of clinical pharmacology research, 2005
There is a growing body of evidence that the renin-angiotensin system (RAS) plays a pivotal role in the pathogenesis of cardiovascular diseases. Indeed, large clinical trials have demonstrated a substantial benefit of the blockade of this system for cardiovascular-organ protection. Although several types of angiotensin II type 1 (AT1) receptor blockers
H, Kakuta +3 more
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There is a growing body of evidence that the renin-angiotensin system (RAS) plays a pivotal role in the pathogenesis of cardiovascular diseases. Indeed, large clinical trials have demonstrated a substantial benefit of the blockade of this system for cardiovascular-organ protection. Although several types of angiotensin II type 1 (AT1) receptor blockers
H, Kakuta +3 more
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[Current topic of next generation of angiotensin II type 1 receptor blockers].
Nihon rinsho. Japanese journal of clinical medicine, 2012Angiotensin receptor blockers(ARBs) are used as the first-choice anti-hypertensives for prevention of multiple organ damage. Recently, the next-generation ARBs have been expected to have more preventive effect for cardiovascular diseases. For example, metabosartans which have a partial agonistic effect of peroxisome proliferator-activated receptor ...
Masaki, Mogi, Masatsugu, Horiuchi
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The antineoplastic effects of angiotensin II type 1 receptor blockers
Journal of Hypertension, 2013openaire +2 more sources