Results 31 to 40 of about 266,977 (390)

Angiotensin II type 1 and type 2 receptor expression in circulating monocytes of diabetic and hypercholesterolemic patients over 3-month rosuvastatin treatment

Cardiovascular Diabetology, 2012
Background In diabetes, a variety of pro-inflammatory cellular changes has been found in various cell types, including monocytes which are known to be involved in all the phases of atherogenesis.
Marino Franca, Maresca Andrea Maria, Cosentino Marco, Castiglioni Luana, Rasini Emanuela, Mongiardi Christian, Maio Ramona C, Legnaro Massimiliano, Schembri Laura, Dentali Francesco, Grandi Anna Maria, Guasti Luigina   +11 more
doaj   +1 more source

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]

, 2014
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita, Barroso, Booz, Bosnyak, Bosnyak, Brosnihan, Bruneval, Bryan, Calo, Campbell, Caroline Fattah, Castro, Chappell, Chappell, Chen, Christopher M. Loughrey, Clare A. McKinney, Clarke, Costa, Crackower, Cushman, De Mello, Dias-Peixoto, Domeier, Dong, Donoghue, Donoghue, Drummer, Faria-Silva, Ferreira, Ferreira, Ferreira, Ferreira, Flores-Munoz, Flores-Munoz, Fomovsky, Fraga-Silva, Fraga-Silva, Freeman, Galis, Gava, Gembardt, Gomes, Graeme Milligan, Grobe, Gusev, Hanke, Hannan, Harmer, Heitsch, Horiguchi, Horiuchi, Hunyady, Inaba, Iwata, Jackman, Jaiswal, Jarajapu, Kaminska, Kassiri, Katada, Kokkonen, Kramkowski, Langeveld, Lautner, Liao, Libby, Liu, Loot, Lovren, Masson, McCollum, Mehta, Mercure, Miura, Mogielnicki, Nakajima, Newby, Ng, Nouet, Ocaranza, Ocaranza, Ocaranza, Patel, Patel, Qi, Ray, Rice, Rodgers, Rodrigues-Machado, Ross, Rowe, Sampaio, Sampaio, Santos, Santos, Schultz Jel, Selvetella, Shah, Sheng-Long, Singh, Sluimer, Stegbauer, Strawn, Stuart A. Nicklin, Tallant, Tesanovic, Tipnis, Turner, Uekama, Varagic, Vickers, Vilas-Boas, Walters, Wang, Weber, West, Wiemer, Yamada, Yang, Zeng, Zhang, Zhao, Zhong   +123 more
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Angiotensin II Type 2 Receptor Blockade Increases Bone Mass [PDF]

Journal of Biological Chemistry, 2009
Renin angiotensin system (RAS) regulates circulating blood volume and blood pressure systemically, whereas RAS also plays a role in the local milieu. Previous in vitro studies suggested that RAS may be involved in the regulation of bone cells. However, it was not known whether molecules involved in RAS are present in bone in vivo.
Yayoi, Izu, Fumitaka, Mizoguchi, Aya, Kawamata, Tadayoshi, Hayata, Testuya, Nakamoto, Kazuhisa, Nakashima, Tadashi, Inagami, Yoichi, Ezura, Masaki, Noda   +8 more
openaire   +3 more sources

Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet [PDF]

, 2017
AIM:To determine the effect of tempol in normal rats fed high salt on arterial pressure and the balance between antagonist components of the renal renin-angiotensin system.METHODS:Sprague-Dawley rats were fed with 8% NaCl high-salt (HS) or 0.4% NaCl ...
Cao, Gabriel Fernando, Choi, Marcelo Roberto, Della Penna, Silvana Lorena, Fernandez, Belisario Enrique, Gorzalczany, Susana Beatriz, Kouyoumdzian, Nicolás Martín, Roson, Maria Ines, Toblli, Jorge Eduardo   +7 more
core   +1 more source

Hypertension: Renin-Angiotensin-Aldosterone System Alterations [PDF]

, 2015
Blockers of the renin-angiotensin-aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the ...
Danser, A.H.J. (Jan), Esch, J.H.M. (Joep) van, Meiracker, A.H. (Anton) van den, Riet, L. (Luuk) te, Roks, A.J.M. (Anton)   +4 more
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Hypotensive Response to Angiotensin II Type 2 Receptor Stimulation in the Rostral Ventrolateral Medulla Requires Functional GABA-A Receptors

Frontiers in Neuroscience, 2017
Objectives: Angiotensin II, glutamate and gamma-aminobutyric acid (GABA) interact within the rostral ventrolateral medulla (RVLM) and the paraventricular nucleus (PVN) modulating the central regulation of blood pressure and sympathetic tone.
Laura Légat, Laura Légat, Laura Légat, Sofie Brouwers, Sofie Brouwers, Sofie Brouwers, Ilse J. Smolders, Alain G. Dupont, Alain G. Dupont, Alain G. Dupont   +9 more
doaj   +1 more source

Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of  ACE2/AT2R/Mas [PDF]

, 2016
High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze, Briones, Ana M., Burns, Kevin, Callera, Glaucia, Correa, Jose, Gutsol, Alexey, He, Ying, Montezano, Augusto C., Moorman, Danielle, Nguyen Dinh Cat, Aurelie, Touyz, Rhian M.   +10 more
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Angiotensin II Type 2 Receptor Gene Transfer Downregulates Angiotensin II Type 1a Receptor in Vascular Smooth Muscle Cells [PDF]

Hypertension, 2002
Two distinct subtypes of angiotensin (Ang) II receptors, type 1 (AT 1 ) and type 2 (AT 2 ), have been identified. Vascular smooth muscle cells (VSMCs) usually express AT 1 receptor. To elucidate the direct effects of the AT 2 receptor on the AT
Xue-Qing, Jin, Noboru, Fukuda, Jin-Zi, Su, Yi-Mu, Lai, Ryo, Suzuki, Yoshiko, Tahira, Hiroto, Takagi, Yukihiro, Ikeda, Katsuo, Kanmatsuse, Hitoshi, Miyazaki   +9 more
openaire   +2 more sources

Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy

Frontiers in Physiology, 2017
Aims: Renal renin-angiotensin system (RAS) plays a pivotal role in the development of diabetic nephropathy (DN). Angiotensin II (Ang II) type 1 receptor (AT1R) blockade elevates (pro)renin, which may bind to (pro)renin receptor (PRR) and exert receptor ...
Lin Zhang, Xiao-Fei An, Xin Ruan, Dong-Dong Huang, Li Zhou, Hong Xue, Li-Min Lu, Ming He   +7 more
doaj   +1 more source

AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction [PDF]

, 2001
To investigate the functional consequences of postinfarct cardiac angiotensin (ANG) type 2 (AT(2)) receptor upregulation, rats underwent coronary artery ligation or sham operation and were infused with ANG II 3-4 wk later, when scar ...
Basdew, M., Danser, A.H.J. (Jan), Saxena, P.R. (Pramod Ranjan), Schoemaker, R.G. (Regien), Schuijt, M.P., Veghel, R. van, Vries, R.R.P. (René) de   +6 more
core   +1 more source