Results 31 to 40 of about 261,219 (287)

Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?

Molecular Medicine, 2020
Infection of lung cells by the corona virus results in a loss of the balance between, on the one hand, angiotensin II-mediated stimulation of the angiotensin II type 1 receptor and, on the other hand, stimulation of the angiotensin II type 2 receptor and/
Pawel Namsolleck, Gert N. Moll
doaj   +1 more source

Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

Biomolecules, 2020
Angiotensin II receptor type 1 and 2 (AT1R and AT2R) are two G-protein coupled receptors that mediate most biological functions of the octapeptide Angiotensin II (Ang II).
Silvana Vasile, Anders Hallberg, Jessica Sallander, Mathias Hallberg, Johan Åqvist, Hugo Gutiérrez-de-Terán   +5 more
doaj   +1 more source

Angiotensin II type 2 receptor inhibits expression and function of insulin receptor in rat renal proximal tubule cells. [PDF]

J Am Soc Hypertens, 2018
Yang Y, Chen C, Fu C, Xu Z, Lan C, Zeng Y, Chen Z, Jose PA, Zhang Y, Zeng C.   +9 more
europepmc   +3 more sources

Evidence for angiotensin II type 2 receptor–mediated cardiac myocyte enlargement during in vivo pressure overload [PDF]

Journal of Clinical Investigation, 2000
Takaaki Senbonmatsu, Sahoko Ichihara, Edward Price, F. Andrew Gaffney, Tadashi Inagami   +4 more
openalex   +2 more sources

Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? [PDF]

Cell Journal, 2022
There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of themare in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cellsthrough the renin-angiotensin
Maryam Barekat, Mohammad Amin Shahrbaf, Kosar Rahi, Massoud Vosough   +3 more
doaj   +1 more source

The effect of aerobic exercise on the function of the local renin-angiotensin system and gluconeogenesis pathway in the liver tissue of type 2 diabetic rats [PDF]

مجله علوم پزشکی فیض (پیوسته), 2023
Background and Aim: One of the important and effective physiological systems in the pathogenesis of type 2 diabetes is the local renin-angiotensin system. The aim of the current study was to determine the effect of aerobic exercise on the function of the
Mohadeseh Shojaei, Fatemeh Kazeminasab, Mohammadjavad Pourvaghar   +2 more
doaj   +2 more sources

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. [PDF]

, 2003
Stimulation of a mutant angiotensin type 1A receptor (DRY/AAY) with angiotensin II (Ang II) or of a wild-type receptor with an Ang II analog ([sarcosine1,Ile4,Ile8]Ang II) fails to activate classical heterotrimeric G protein signaling but does lead to ...
Ahn, S, Hunyady, L, Karnik, SS, Lefkowitz, RJ, Luttrell, LM, Shenoy, SK, Wei, H   +6 more
core   +2 more sources

Angiotensin II type 1 and type 2 receptor expression in circulating monocytes of diabetic and hypercholesterolemic patients over 3-month rosuvastatin treatment

Cardiovascular Diabetology, 2012
Background In diabetes, a variety of pro-inflammatory cellular changes has been found in various cell types, including monocytes which are known to be involved in all the phases of atherogenesis.
Marino Franca, Maresca Andrea Maria, Cosentino Marco, Castiglioni Luana, Rasini Emanuela, Mongiardi Christian, Maio Ramona C, Legnaro Massimiliano, Schembri Laura, Dentali Francesco, Grandi Anna Maria, Guasti Luigina   +11 more
doaj   +1 more source

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]

, 2014
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita, Barroso, Booz, Bosnyak, Bosnyak, Brosnihan, Bruneval, Bryan, Calo, Campbell, Caroline Fattah, Castro, Chappell, Chappell, Chen, Christopher M. Loughrey, Clare A. McKinney, Clarke, Costa, Crackower, Cushman, De Mello, Dias-Peixoto, Domeier, Dong, Donoghue, Donoghue, Drummer, Faria-Silva, Ferreira, Ferreira, Ferreira, Ferreira, Flores-Munoz, Flores-Munoz, Fomovsky, Fraga-Silva, Fraga-Silva, Freeman, Galis, Gava, Gembardt, Gomes, Graeme Milligan, Grobe, Gusev, Hanke, Hannan, Harmer, Heitsch, Horiguchi, Horiuchi, Hunyady, Inaba, Iwata, Jackman, Jaiswal, Jarajapu, Kaminska, Kassiri, Katada, Kokkonen, Kramkowski, Langeveld, Lautner, Liao, Libby, Liu, Loot, Lovren, Masson, McCollum, Mehta, Mercure, Miura, Mogielnicki, Nakajima, Newby, Ng, Nouet, Ocaranza, Ocaranza, Ocaranza, Patel, Patel, Qi, Ray, Rice, Rodgers, Rodrigues-Machado, Ross, Rowe, Sampaio, Sampaio, Santos, Santos, Schultz Jel, Selvetella, Shah, Sheng-Long, Singh, Sluimer, Stegbauer, Strawn, Stuart A. Nicklin, Tallant, Tesanovic, Tipnis, Turner, Uekama, Varagic, Vickers, Vilas-Boas, Walters, Wang, Weber, West, Wiemer, Yamada, Yang, Zeng, Zhang, Zhao, Zhong   +123 more
core   +1 more source

Angiotensin II Type 2 Receptor Overexpression Preserves Left Ventricular Function After Myocardial Infarction [PDF]

Circulation, 2002
Zequan Yang, Christina M. Bové, Brent A. French, Frederick H. Epstein, Stuart S. Berr, Joseph M DiMaria, Jennifer Gibson, Robert M. Carey, Christopher M. Kramer   +8 more
openalex   +2 more sources