Results 41 to 50 of about 192,985 (344)

Angiotensin Receptor Blocker (ARB): Is it Effective to Prevent Cerebral Malaria? [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases
Cerebral malaria is a severe complication of plasmodium falciparum infection with 15-25% mortality rates. Sequestration of infected red blood cells disrupts the blood brain barried leading to irreversible brain damage, impacting quality of life.
I Gusti Ayu Hiranandini Prawista, Davin Beta Tadeo, I Gusti Ngurah Ariestha Satya Diksha, Darren Junior, Richard Christian Suteja, Cokorda Agung Wahyu Purnamasidhi, Saktivi Harkitasari   +6 more
doaj   +1 more source

Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy [PDF]

, 2007
Maternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor.
Kellems, Rodney E., Kellems, Rodney E, Mi, TieJuan, Xia, Yang, Sun, C, Hewett, Peter W, Abbasi, S, Zhou, CC, Mi, T, Abbasi, Shahrzad, Hewett, Peter, Xia, Y, Sun, ChunXiao, Kellems, RE, Ahmed, Asif, Hewett, Peter W., Xia, L, Ahmad, Shakil, Xia, Lingwei, Zhou, Cissy Chenyi   +19 more
core   +1 more source

Angiotensin II type 2 receptor–interacting protein 3a inhibits ovarian carcinoma metastasis via the extracellular HMGA2-mediated ERK/EMT pathway

Tumor Biology, 2017
Local migration and long-distance metastasis is the main reason for higher mortality of ovarian cancer. Microtubule-associated tumor suppressor 1/angiotensin II type 2 receptor–interacting protein is associated with tumor initiation and progression and ...
Ping Huang, Liang Guo, Jie Xi, Donghui Wang   +3 more
doaj   +1 more source

Effects of telmisartan and ramipril on adiponectin and blood pressure in patients with type 2 diabetes [PDF]

, 2008
<b>Background:</b> Adiponectin is secreted by adipose tissue and may play a role in cardiovascular disease. We examined adiponectin levels in patients with type 2 diabetes who participated in the Telmisartan vs.
Fauvel, J.P., Raff, U., R. E. Schmieder, C. Delles, Ruilope, L.M., Mimran, A., J. P. Fauvel, Delles, C., U. Raff, A. Mimran, Schmieder, R.E., L. M. Ruilope   +11 more
core   +1 more source

Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy

Frontiers in Physiology, 2017
Aims: Renal renin-angiotensin system (RAS) plays a pivotal role in the development of diabetic nephropathy (DN). Angiotensin II (Ang II) type 1 receptor (AT1R) blockade elevates (pro)renin, which may bind to (pro)renin receptor (PRR) and exert receptor ...
Lin Zhang, Xiao-Fei An, Xin Ruan, Dong-Dong Huang, Li Zhou, Hong Xue, Li-Min Lu, Ming He   +7 more
doaj   +1 more source

Hypotensive Response to Angiotensin II Type 2 Receptor Stimulation in the Rostral Ventrolateral Medulla Requires Functional GABA-A Receptors

Frontiers in Neuroscience, 2017
Objectives: Angiotensin II, glutamate and gamma-aminobutyric acid (GABA) interact within the rostral ventrolateral medulla (RVLM) and the paraventricular nucleus (PVN) modulating the central regulation of blood pressure and sympathetic tone.
Laura Légat, Laura Légat, Laura Légat, Sofie Brouwers, Sofie Brouwers, Sofie Brouwers, Ilse J. Smolders, Alain G. Dupont, Alain G. Dupont, Alain G. Dupont   +9 more
doaj   +1 more source

The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.

Structure, 2019
Angiotensin II (AngII) is a peptide hormone that plays a key role in regulating blood pressure, and its interactions with the G protein-coupled receptors, AngII type-1 receptor (AT1R) and AngII type-2 receptor (AT2R), are central to its mechanism of ...
H. Asada, A. Inoue, Francois Marie Ngako Kadji, K. Hirata, Y. Shiimura, D. Im, T. Shimamura, N. Nomura, H. Iwanari, T. Hamakubo, Osamu Kusano-Arai, Hiromi Hisano, Tomoko Uemura, C. Suno, J. Aoki, S. Iwata   +15 more
semanticscholar   +1 more source

Hypoxia-induced signaling in angiogenesis : role of mTOR, HIF and Angiotensin II [PDF]

, 2007
This thesis includes the work of four different projects I have been following during my time as a PhD student; (1) the characterization of mTOR-associated signaling and endothelial cell proliferation in response to hypoxia, and (2) identification of ...
Petrimpol, Marco Renato
core   +1 more source

The angiotensin II type 2 receptor in cardiovascular disease

Journal of the Renin-Angiotensin-Aldosterone System, 2009
Angiotensin II (Ang II) is considered the major final mediator of the renin-angiotensin system. The actions of Ang II have been implicated in many cardiovascular conditions, such as hypertension, atherosclerosis, coronary heart disease, restenosis, and heart failure. Ang II can act through two different receptors: Ang II type 1 (AT
Catherine A, Lemarié, Ernesto L, Schiffrin   +1 more
openaire   +2 more sources

Cardiovascular and renal function of angiotensin II type-2 receptors [PDF]

Cardiovascular Research, 2004
While all of the well-known cardiovascular and renal effects of angiotensin II (ANG) are attributed to the ANG type-1 (AT(1)) receptor, much less is known about the function of ANG type-2 (AT(2)) receptors. This review focuses on progress made in AT(2) receptor research over the past 10 years mainly enabled by the availability of AT(2) receptor ...
Olaf, Jöhren, Andreas, Dendorfer, Peter, Dominiak   +2 more
openaire   +2 more sources