Results 31 to 40 of about 2,698 (247)
Journal of Veterinary Internal Medicine, 2022 Background Activity of the circulating renin‐angiotensin‐aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and the effects of furosemide or amlodipine treatment on the ...
Jessica L. Ward +5 more
doaj +1 more source
Effects of truncated angiotensins in humans after double blockade of the renin system
, 2003 Bie. Effects of truncated angiotensins in humans after dou-ble blockade of the renin system.
Bie, Peter +20 more
core +1 more source
G protein coupled receptors of the renin-angiotensin system: new targets against breast cancer?
Frontiers in Pharmacology, 2015 G-protein coupled receptors (GPCRs) constitute the largest family of membrane receptors, with high potential for drug discovery. These receptors can be activated by a panel of different ligands including ions, hormones, small molecules and vasoactive ...
Clara eNAHMIAS +1 more
doaj +1 more source
The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19
Frontiers in Pharmacology, 2021 The renin-angiotensin-aldosterone system (RAAS) firstly considered as a cardiovascular circulating hormonal system, it is now accepted as a local tissue system that works synergistically or independently with the circulating one.
Annamaria Mascolo +16 more
doaj +1 more source
, 1988 To prevent in vitro generation of angiotensins, the renin inhibitor CGP 29287 (CGP) was added to blood sampling tubes. Plasma immunoreactive angiotensin (ir-ANG) I and II were simultaneously measured by radioimmunoassay after rapid and quantitative ...
Brunner HR +3 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Angiotensins and Alzheimer's disease: a bench to bedside overview
, 2009 The pathology of Alzheimer's disease (AD) features amyloid beta peptide deposition, intracellular neurofibrillary tangles and deficits in the cholinergic pathway.
Kehoe, Patrick G
core +1 more source
Cardiac renin and angiotensins: uptake from plasma versus in situ synthesis [PDF]
, 1994 The existence of a cardiac renin-angiotensin system, independent of the circulating renin-angiotensin system, is still controversial. We compared the tissue levels of renin-angiotensin system components in the heart with the levels in blood plasma in ...
Verdouw, PD +7 more
core +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Focus on Brain Angiotensin III and Aminopeptidase A in the Control of Hypertension
International Journal of Hypertension, 2012 The classic renin-angiotensin system (RAS) was initially described as a hormone system designed to mediate cardiovascular and body water regulation. The discovery of a brain RAS composed of the necessary functional components (angiotensinogen, peptidases,
John W. Wright +2 more
doaj +1 more source