Results 11 to 20 of about 6,398 (200)

REPRODUCTIVE ORGAN DAMAGE OF DOMESTIC RUMINANTS IN AFRICAN ANIMAL TRYPANOSOMIASIS: A REVIEW

FUDMA Journal of Agriculture and Agricultural Technology, 2022
Animal African trypanosomiasis affects both production and reproduction in domestic ruminants. The reproductive damages caused by trypanosomes have direct or indirect link to some specific organs like endocrine and pituitary gland which secrets follicle stimulating hormone (FSH), interstitial-cell stimulating hormone (ICSH) and growth hormone (GH ...
A. A. AJAKAIYE, M. A. ABDULLAHI, T. O. OLANREWAJU   +2 more
openalex   +3 more sources

Pharma to farmer: field challenges of optimizing trypanocide use in African animal trypanosomiasis [PDF]

Trends in Parasitology, 2021
Trypanocides are a key control component of African animal trypanosomiasis (AAT) in tsetse-infested areas of sub-Saharan Africa. While farmers are dependent upon trypanocides, recent research highlights their inappropriate and ineffective use, problems with drug quality, and treatment failure.
Shauna Richards, Liam J. Morrison, Stephen J. Torr, Michael P. Barrett, Oliver Manangwa, Furaha Mramba, Harriet Auty   +6 more
openalex   +5 more sources

African animal trypanosomiasis as a constraint to livestock health and production in Karamoja region: a detailed qualitative and quantitative assessment [PDF]

BMC Veterinary Research, 2017
Background Nagana (African Animal Trypanosomiasis-AAT) and tick-borne diseases (TBDs) constrain livestock production in most parts of sub-Saharan Africa.
Dennis Muhanguzi, Albert Mugenyi, Godfrey Bigirwa, Maureen Kamusiime, Ann Kitibwa, Grace Gloria Akurut, Sylvester Ochwo, Wilson Amanyire, Samuel George Okech, Jan Hattendorf, Robert Tweyongyere   +10 more
doaj   +2 more sources

Tsetse and African Animal Trypanosomiasis status; prevalence, spatial distribution, and implications to control trypanosomiasis in Uganda [PDF]

Tropical Animal Health and Production
Abstract African animal trypanosomiasis (AAT) transmitted by tsetse flies poses a threat to livestock in Uganda. The disease has been present in the country for many years. Mapping of the disease prevalence and vector spatial distribution in the country was undertaken to assess the situation.
Mandela Robert Wangoola, Geofrey Ogwal, Henry Magambo, Patrick Bingi, Moses Kasawe, Aisha Umat Nampala   +5 more
openalex   +3 more sources

Modelling to infer the role of animals in gambiense human African trypanosomiasis transmission and elimination in DRC [PDF]

PLOS Neglected Tropical Diseases, 2021
Gambiense human African trypanosomiasis (gHAT) has been targeted for elimination of transmission (EoT) to humans by 2030. Whilst this ambitious goal is rapidly approaching, there remain fundamental questions about the presence of non-human animal transmission cycles and their potential role in slowing progress ...
R. E. Crump, Ching-I Huang, Simon E. F. Spencer, Paul E. Brown, Chansy Shampa, Erick Mwamba Miaka, Kat S. Rock   +6 more
openalex   +5 more sources

Bovine and small ruminant African animal trypanosomiasis in Nigeria – A review

Veterinary Parasitology: Regional Studies and Reports, 2018
Despite extensive attempts over many decades to control African Animal Trypanosomiasis (AAT) across the tsetse fly belt of Nigeria, AAT persists as major animal health problem causing severe morbidity and mortality in livestock. The large agricultural losses in turn have severe adverse impacts on sustainable agricultural development.
Paul Olalekan Odeniran, Isaiah Oluwafemi Ademola, Ewan T. MacLeod, Susan C. Welburn   +3 more
openalex   +6 more sources

Cloning and Characterization of Trypanosoma congolense and T. vivax Nucleoside Transporters Reveal the Potential of P1-Type Carriers for the Discovery of Broad-Spectrum Nucleoside-Based Therapeutics against Animal African Trypanosomiasis. [PDF]

Int J Mol Sci, 2023
Ungogo MA, Aldfer MM, Natto MJ, Zhuang H, Chisholm R, Walsh K, McGee M, Ilbeigi K, Asseri JI, Burchmore RJS, Caljon G, Van Calenbergh S, De Koning HP.   +12 more
europepmc   +3 more sources

Mathematical Model for Describing the Transmission of Animal African Trypanosomiasis in Cattle

Asian Research Journal of Mathematics
In this paper, we have formulated a mathematical model for the transmission dynamics of African Animal Trypanosomiasis (AAT) by incorporating spraying of the tsetse y population(vector) and treating the cattle population (host) as control strategies.
Conrad Akello, David Ambogo, Richard Opiyo   +2 more
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Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species [PDF]

Trends in Parasitology, 2016
Animal African trypanosomiasis (AAT), caused by Trypanosoma congolense and Trypanosoma vivax, remains one of the most important livestock diseases in sub-Saharan Africa, particularly affecting cattle. Despite this, our detailed knowledge largely stems from the human pathogen Trypanosoma brucei and mouse experimental models.
Liam J. Morrison, Laura Vezza, T.G. Rowan, Jayne C. Hope   +3 more
openalex   +5 more sources

Biological and pharmacological investigations of novel diamidines in animal models of human African trypanosomiasis [PDF]

, 2013
"African sleeping sickness, also called human African trypanosomiasis (HAT), results from the infection of humans with either of two protozoan parasites, Trypanosoma brucei gambiense and T. b. rhodesiense. HAT is transmitted by tsetse flies (Glossina spp) and, like the vector, is found exclusively in Africa between the latitudes 14° North and 29° South.
John Thuita Kibuthu
openalex   +4 more sources